ID A0A3P8US47_CYNSE Unreviewed; 816 AA.
AC A0A3P8US47;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Non-canonical poly(A) RNA polymerase PAPD7-like {ECO:0000313|Ensembl:ENSCSEP00000006023.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000006023.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000006023.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000006023.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008321472.1; XM_008323250.2.
DR AlphaFoldDB; A0A3P8US47; -.
DR STRING; 244447.ENSCSEP00000006023; -.
DR Ensembl; ENSCSET00000006088.1; ENSCSEP00000006023.1; ENSCSEG00000003887.1.
DR GeneID; 103388317; -.
DR KEGG; csem:103388317; -.
DR GeneTree; ENSGT00940000157811; -.
DR InParanoid; A0A3P8US47; -.
DR OMA; NQFLHYG; -.
DR OrthoDB; 21395at2759; -.
DR Proteomes; UP000265120; Chromosome 13.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR PANTHER; PTHR23092:SF24; TERMINAL NUCLEOTIDYLTRANSFERASE 4A; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 259..368
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 421..481
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 77..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..635
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..173
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..190
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 91234 MW; A5E47EBBE679D45C CRC64;
MDPRTAWIQP EQKGPANSLW MHIWETSQGF GANSHIDNHL HLQRNFAVHN SNSADSHGEY
YKNVTPPPPA VVFEKLAKRG GGGDRGSVRR KGSLSPSSSS LDSEAESSSP SGSSLQIDNL
NVAEEASRFL HYSEHELNGN NLRRQYPPPP FHGVQQHCRS MQQSSGHTPT GMKSQHGNKH
HHLQPHSSGR RRHLNRANTF HGINPLLSFN GHYGDSSSSL WKTRRYSPGI NGLHEEIVDF
FNFMSPRPEE EAMRRDVVNR IESVIKDLWP TARVEIFGSF STGLYLPTSD IDLVVFGKWD
HPPLQELEQA LKKRNVAGTY PIKVLDKATV PIIKLTDHET EVKVDISFNV ETAVKAAQFI
KSYLKKYTVL PPLIFVLKQF LLQRDLNEVF TGGISSYSLI LMAISFLQLH PRIDTRRSNI
NLGILLIEFF ELYGHDFNYM KTGIRVKNGG AYMSKEEMLK AMGSGNRTSM LCIEDPIQPG
NDVGRSSYGV LQVKQVFDFA YMVLSHGVSS LARAYPNKDY DSTLGRIIKV SPEVLAYRDW
TIKKWGAKQY AKHQENQVSS LSDIETCEQD LARLMLVSVE DQRDSSSPLS ADSPSPPPVF
LPSPQHHSSS SSACSLSSSS GSDIESDSPP NSNATIQLHP LTLASVHPMI QMATDLRATH
AGFIHAMSQV QMSLPENLTI PSLSECQFYH ENPPSISVVH RHTSQAAPIS QHGNSTNPLP
SPIHRLHPTL PGGQQSHTYV MRSNSQGSIE PHKLSFKHNQ GSVLQNQNPS QGNFSQQRFV
PQGTSPTVGF RNQQQYNRNT WRRRKRDDPT ALNQSR
//
