ID A0A3P8UTF4_CYNSE Unreviewed; 549 AA.
AC A0A3P8UTF4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Protein NDNF {ECO:0000256|ARBA:ARBA00024096};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000005657.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000005657.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000005657.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR AlphaFoldDB; A0A3P8UTF4; -.
DR Ensembl; ENSCSET00000005717.1; ENSCSEP00000005657.1; ENSCSEG00000003652.1.
DR GeneTree; ENSGT00390000007586; -.
DR InParanoid; A0A3P8UTF4; -.
DR OMA; ASVKMQT; -.
DR Proteomes; UP000265120; Chromosome 12.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019326; NDNF.
DR InterPro; IPR045805; NDNF_C.
DR PANTHER; PTHR14619; NEURON-DERIVED NEUROTROPHIC FACTOR; 1.
DR PANTHER; PTHR14619:SF2; PROTEIN NDNF; 1.
DR Pfam; PF10179; NDNF; 1.
DR Pfam; PF19433; NDNF_C; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..549
FT /note="Protein NDNF"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018077164"
FT DOMAIN 171..318
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|SMART:SM00060"
FT DOMAIN 458..535
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|SMART:SM00060"
SQ SEQUENCE 549 AA; 61892 MW; 13C4976A72B9F12C CRC64;
MALTSLPWYC AALVLFYSSP WPQVHTAVAP ENEVPLRPTV WIQEGKVTSV NLHKGRTRRL
YFTLRKKSPG LSVSVSPCDQ AIDWSLAART LKDKPFKSLQ WSSKKSVPEV WWHGPGSEEK
LYSFTGITED TYRGPSYPQA SVYILRLRSK LHNTRATVSF HEGLGPSGTF PLLPADPRVH
TLGVGMTSVT LSWAPSASIT NLHQSQKSYY YCVLVNPEQN FPSLCAAQEN KKSEKRQKLD
KKQKKKRKVT EWPIVKEPWW QQEDDSYPKD QPSSLADELS DPQCVCRGTE SVCTISELLP
DTQYYFDVFV MDRLNGTSSA YKGTFARTHE EANPAIGTLK EGELRWVTFK DAGSTSEQFF
TFRPRGWQQS GLLTLQSCSE EEKVQVTVSS KSRVLTSQNV GVEVVHIWLH GSSSYLVHLR
REGTISKGST TTDLARPGGL TASVKMQSSS AYHRKGIPSL PSTLQIKSFN RLRSCNSVTL
AWMGTEERSL FCVYSRKYFQ ELNPHRAVTT AVIGGLEPGM AYVFDVYLMR RWGIPIKYAS
KVVKTRKEC
//
