ID A0A3P8UWJ7_CYNSE Unreviewed; 1240 AA.
AC A0A3P8UWJ7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Apoptotic chromatin condensation inducer in the nucleus-like {ECO:0000313|Ensembl:ENSCSEP00000006747.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000006747.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000006747.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000006747.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8UWJ7; -.
DR STRING; 244447.ENSCSEP00000006747; -.
DR Ensembl; ENSCSET00000006821.1; ENSCSEP00000006747.1; ENSCSEG00000004364.1.
DR GeneTree; ENSGT00710000106790; -.
DR InParanoid; A0A3P8UWJ7; -.
DR OMA; DYHKGIR; -.
DR Proteomes; UP000265120; Chromosome 1.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd12432; RRM_ACINU; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR034257; Acinus_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR032552; RSB_motif.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR46589; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR PANTHER; PTHR46589:SF1; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR Pfam; PF16294; RSB_motif; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 13..47
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 98..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 956..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1038..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1107..1240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..121
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 249..268
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 282..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..342
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..358
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 368..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..430
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..546
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..774
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..799
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..1002
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1063..1081
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1184..1215
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1240 AA; 138091 MW; 65ACFBCFB8B5F0C1 CRC64;
MADEDITLDG KPLQSLRVAD LKAALEQRNL PKSGQKNTLV KRLKGALMLE NLQKTSSSHM
HSGLQPNSQI GEEMCQNSFI KQYLAKQQEL LRQRLEREAT QNDEADESPS VPEEDEEHSE
DNDSPSCVTE KNCPIPSHST LTRPGRAVSA AVVGHGFMSI QSQESPEALQ TRVQRAVGHQ
EPVPSPPRAV ASLSVRILGE ADRQGLPPAV PRVYEKEGTA PSQPGSAQSV LHLSRSAGVT
AGSVVLKDSS DDDDDDDDGD DECEDDEDWG SQPGKGKTVP PKPQQMPSTM LSSGGRSKRK
LQVPQHIPPP QAQHSPMQLR HPTPPPSPPS NLFPLPDTPK QSPPEPDDQD RDVAEPALDR
RAASFLPPSV QMQDSDSSSG SSSPDPPAKS KPGPLSLLVH KMESEGAFQA SMEMSEDTSH
STAGSSSESP LQKLKKKRQE ENIETEVETQ LKKVKERGGQ QVREREEHYS EEKKKDREKE
QHQYKENMET KLNTAENEGR GKKTQDEVEI KEESGLKEEK DMRQKTANRD RKVMTKQRES
DSSDSDSKSD SASQSSSSSS DKTLSARQNK LLGQTHKQKV EEEHKTTLTE EVKKRHLSTR
EVSEPSAAAV TEVEPDSESS MADQPASGAE PENSENRLEE STTTKAFAAR KISLTNPKTS
PATTDGGGAG EGEAGVAAGR KRRWGSSTAV TAKKPSISIT TESLKSLIPD IKLEAVVDLH
PEELQLSGDE GKQENNHSDE DKGLKIRRTV TQVVQGDTQE NGQEEDDEEE EVQEQVEKME
KTEKEKHSSR DRRKSSVSEE TSESQTFANM DGDVKKVTPR DSLVRRSISQ QKSGVSVTID
DPVCAVKQPS PPRGQISKII HVTNLVRPFT LGQLKELLNR TGSVLEDGFW IDKIKSHCYV
TYATTEEAVS TRNAIHGVKW PSSNPKVLSV DFCGQDELDF HRGILKPEKE VEHIQVQAPG
APHNRLPPLM PERDRDRERE RDRDRDREEK DREHERDRER GAAGVRDIWA EREREMERRE
RARGEREWDR DKIREYAGPG EDERRSRSRE RERRRRERAR SKERKTDKKE KGDEPPAKLL
DDLFLKTKAP PCIYWLPLTE EQAAQRLLDR TERQKERERR RKEQQEEEDK KREEEKKERL
KIREKDGGGG GGSAGGGGSG GGGGGGGSGG SAAGSAAINR GADRRGTNGD REREKERERG
RDKEGDTRRD SGGHRPQRLS GGPGSGRRSR SRSNPRDRRR
//
