ID A0A3P8UWU1_CYNSE Unreviewed; 453 AA.
AC A0A3P8UWU1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Transcription factor Sp8 {ECO:0000313|Ensembl:ENSCSEP00000007663.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000007663.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000007663.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000007663.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008321584.2; XM_008323362.2.
DR AlphaFoldDB; A0A3P8UWU1; -.
DR STRING; 244447.ENSCSEP00000007663; -.
DR Ensembl; ENSCSET00000007743.1; ENSCSEP00000007663.1; ENSCSEG00000004940.1.
DR GeneID; 103388406; -.
DR KEGG; csem:103388406; -.
DR CTD; 324931; -.
DR GeneTree; ENSGT00940000162033; -.
DR InParanoid; A0A3P8UWU1; -.
DR OMA; QNPNGVH; -.
DR OrthoDB; 5359201at2759; -.
DR Proteomes; UP000265120; Chromosome 13.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd22538; SP8_N; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23235; KRUEPPEL-LIKE TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR23235:SF25; TRANSCRIPTION FACTOR SP8; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 318..347
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 348..377
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 378..405
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 257..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 46938 MW; 5223B600778979D5 CRC64;
MATSLLGEEP RLGSTPLAML AATCNKIGSP SPSPSAISDN SSSFGKGFHP WKRAAASSCS
LGSGLSGFGV SRNGSGISDS FGTNSPSGSS AFSLTSGTTS SSHFGNDYSV FQASVSSGSQ
ESSHQPVFIS KVHTSVDSLQ GIYPRMSVAH PYESWFKSSH PGIPTAGDVG TTGASAWWDV
GAGWIDVQNP NGAALQTSLH SGGLQTSLHS PLGGYNSDYS SLSHSAFSTS PSPHLLTSGQ
HLMDGFKPVL SSYPDSTPSP LAGAGGTMLS GGPPASLAGS PRSSARRYSG RATCDCPNCQ
EAERLGPAGA SLRRKGLHSC HIPGCGKVYG KTSHLKAHLR WHTGERPFVC NWLFCGKRFT
RSDELQRHLR THTGEKRFAC PVCNKRFMRS DHLSKHVKTH SAGGSAGSGS GGSGGKRGSD
TDSEHSAPGS PPCHSPDLLH PPESTQGVGM NGL
//
