ID A0A3P8V091_CYNSE Unreviewed; 633 AA.
AC A0A3P8V091;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Coiled-coil domain-containing protein 22 {ECO:0000256|ARBA:ARBA00016694};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000007504.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000007504.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000007504.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CCDC22 family.
CC {ECO:0000256|ARBA:ARBA00006438}.
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DR RefSeq; XP_008316722.1; XM_008318500.2.
DR AlphaFoldDB; A0A3P8V091; -.
DR STRING; 244447.ENSCSEP00000007504; -.
DR Ensembl; ENSCSET00000007583.1; ENSCSEP00000007504.1; ENSCSEG00000004843.1.
DR GeneID; 103384822; -.
DR KEGG; csem:103384822; -.
DR CTD; 28952; -.
DR GeneTree; ENSGT00390000003809; -.
DR InParanoid; A0A3P8V091; -.
DR OMA; KFEQHIQ; -.
DR OrthoDB; 9179at2759; -.
DR Proteomes; UP000265120; Chromosome 10.
DR InterPro; IPR008530; CCDC22.
DR InterPro; IPR048348; CCDC22_CC.
DR InterPro; IPR048349; CCDC22_N.
DR PANTHER; PTHR15668:SF4; COILED-COIL DOMAIN-CONTAINING PROTEIN 22; 1.
DR PANTHER; PTHR15668; JM1 PROTEIN; 1.
DR Pfam; PF05667; CCDC22_CC; 1.
DR Pfam; PF21674; CCDC22_N; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 1..109
FT /note="CCDC22 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21674"
FT DOMAIN 128..602
FT /note="CCDC22 coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF05667"
FT REGION 257..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 71947 MW; A52D545B6C316BFF CRC64;
MEEVDKILIH ALKQIGTDVS EEISSINQFS SELIVKAVVR CIQVINPGLG SPLPSSLPPA
MSARFRVGMS LAQACQELGY KGEIGYQTFL YSSELEIRSL LMFLVEKLPR ESSEASDQPT
GKSVVLQRAI AAAIKAQLSV PWLPMNCRLP LHTETQSAGP LHSFHTLPLS LPYSSTGLGD
KYEKEEKEYQ RDFLLPVTAQ ISHQPSMVAS ILEHHTTVLS AVQQWDNEWN SQGLLSRLTP
QEYRARKMAR LRKRIKEQLR SNAHPSPEGS FRSSHSSNDL SEVLQMFKSP SSSDHILTKG
THFTHTQKFT FEQEPAAVTS PVPTGRQSDG DVQQRQQAEI ESLQQQLQQL CTEIEQLTTD
MKHMSVTHTQ VLNEIKQKEL MNKETEDKIQ VKKKTLDFLP DSDNSLQKLQ AQVEASAARL
VNLASQWEKH RAPLIEEHRR LKEKCSNQEL ESSRKLSEIK SMQEKIRVAT EEARKKEDIH
KQLVTQLENL PKDVSRSAYT QRILEIVSNI KKQKEEINKI LSDTRELQKE INSLTGKLDR
TFAVTDELVF KDAKKDESVR KSYKYLAALH DNCNQLIQTI EETGTILREI RDLEEQIETE
NSNKTVANLE RILEDYKAIR QENSVLAAKI KEG
//
