ID A0A3P8V413_CYNSE Unreviewed; 943 AA.
AC A0A3P8V413;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=BicC family RNA binding protein 1 {ECO:0000313|Ensembl:ENSCSEP00000007846.1};
GN Name=BICC1 {ECO:0000313|Ensembl:ENSCSEP00000007846.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000007846.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000007846.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000007846.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicC family.
CC {ECO:0000256|ARBA:ARBA00007662}.
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DR AlphaFoldDB; A0A3P8V413; -.
DR Ensembl; ENSCSET00000007931.1; ENSCSEP00000007846.1; ENSCSEG00000005038.1.
DR GeneTree; ENSGT00940000156276; -.
DR OMA; PDNDTPY; -.
DR Proteomes; UP000265120; Chromosome 12.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22421; KH-I_BICC1_rpt2; 1.
DR CDD; cd22422; KH-I_BICC1_rpt3; 1.
DR CDD; cd09520; SAM_BICC1; 1.
DR Gene3D; 3.30.310.270; -; 2.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR047554; BICC1_KH-I_rpt2.
DR InterPro; IPR047553; BICC1_KH-I_rpt3.
DR InterPro; IPR037974; BICC1_SAM_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR10627:SF78; PROTEIN BICAUDAL C HOMOLOG 1; 1.
DR PANTHER; PTHR10627; SCP160; 1.
DR Pfam; PF00013; KH_1; 2.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50084; KH_TYPE_1; 2.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 843..906
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..590
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 943 AA; 101681 MW; 8C5DAFF485941672 CRC64;
MAAQCDTLSG YLQQSDQGSN SERSTDSPLP GSEEDLSGPH PLPDPEWTEE RFRVDRKKLE
IMLLDPHIKV CGKRENVREA KDRIMSVLDT KSNRVTLKMD VSHTEHSHVI GKGGNNIKRV
MEETGCHIHF PDSNRNNQTE KSNQVSIAGQ PGGVEAARMK IRELLPLVLS FELPAIMQSD
PSSPTVQHIS QTYNLTVSFK PPTRLYRATG VVRGSQNNVN AVKRGTALLL EHLAGSLAST
ISVTTHLDIA PQHHLFMKGR NGSNIKHITQ RTGAQIHFPD PNGPQKKSTV YIQGTIESVC
LARQYLMGCL PLVLMFDIKE DIEVDPQCIT VLMEQLDVFI SIKPKPKQPS KSVIVKSVER
NAVNMYEARR FLLGLESNGV SLTSSSLSSS PSVALNPTNS GPSASLICPV GLDILASAGL
GLSNLGFLGA AAPHSLTTSA APNAVLNSLN SSMSPLQTPS PSTPTASPSL WPSSLTGTQG
FSSPLMLHAA TQATLSSILL SGVQGYTQST PSPPPGLAPI DKQTNGVPDC SKVPCTLNGH
VKHPASVYGR IATASLAETV RNPAPCDSVQ EASGHSPSEP LSSKSNPDEG SDTFVEVGMP
RSPSHSANGS ELKQMLASCK TSSGKRQAVE LLQGTKNSHL HSDCLLSDAE SSSSDSPVAD
KRAPGSERAA ERAAQQNERE RIRLAPQTSF ANMQAFDYEQ KKLLATKAML KKPVVTEVRT
PTNTWSGLGF SKSMPAETIK ELRRANHVSY KPSMTTTYEG SPLSLSRSSS REGVGNGSDS
DNWRERNGTG NGLPSHTEFP SAVSSPKRKQ NKSAAEHYLS SSNYMDCIPS VTGSNGCSLS
SSLKGSDLPE LFSKLGLGKY TDVFQQQEID LQTFLTLTDQ DLKELGITTF GARRKMLLAI
SELNKNQRKF FEPPIRSSFL EGGASGRLSR QFHTDMASVS GRW
//
