ID   A0A3P8V6J2_CYNSE        Unreviewed;       623 AA.
AC   A0A3P8V6J2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Kelch repeat and BTB domain containing 7 {ECO:0000313|Ensembl:ENSCSEP00000009724.1};
OS   Cynoglossus semilaevis (Tongue sole).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC   Cynoglossinae; Cynoglossus.
OX   NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000009724.1, ECO:0000313|Proteomes:UP000265120};
RN   [1] {ECO:0000313|Ensembl:ENSCSEP00000009724.1, ECO:0000313|Proteomes:UP000265120}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24487278;
RA   Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA   Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA   Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA   Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA   Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA   Zhao Y., Schartl M., Tang Q., Wang J.;
RT   "Whole-genome sequence of a flatfish provides insights into ZW sex
RT   chromosome evolution and adaptation to a benthic lifestyle.";
RL   Nat. Genet. 46:253-260(2014).
RN   [2] {ECO:0000313|Ensembl:ENSCSEP00000009724.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_008326644.1; XM_008328422.2.
DR   AlphaFoldDB; A0A3P8V6J2; -.
DR   STRING; 244447.ENSCSEP00000009724; -.
DR   Ensembl; ENSCSET00000009837.1; ENSCSEP00000009724.1; ENSCSEG00000006241.1.
DR   GeneID; 103391937; -.
DR   KEGG; csem:103391937; -.
DR   CTD; 84078; -.
DR   GeneTree; ENSGT00940000164962; -.
DR   InParanoid; A0A3P8V6J2; -.
DR   OMA; DLSSQDY; -.
DR   OrthoDB; 5472491at2759; -.
DR   Proteomes; UP000265120; Chromosome 16.
DR   CDD; cd18273; BTB_POZ_KBTBD6_7; 1.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR047933; KBTBD6_7_BTB_POZ.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR   PANTHER; PTHR24412:SF23; KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 7; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 1.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 2.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          37..121
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          586..623
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        608..623
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   623 AA;  70317 MW;  014C0474ABA905BA CRC64;
     MASALSGFGG PEVLEDVNHA RGLITELKSL YDSRLLGDVT IEVECEEEPL LDVGGSALGE
     ADRVFLCSRN ILAAASPYFK SMFTGGLNES VQKRVVIRGV DSESMSVIVD YCYTGRVTVT
     EGNVQRLYAA ANMLQLEYIR KACSGFMSRR LDLSNCVGIL RFADTFDNPE LKESAHAFIA
     RNFNQLCTGG ELCELDLVQL KELLCLDTLD VDCERKVCSA ALQWIEANAP QRRDDALQVF
     KCVRWNLFTE KDRCFLEDLM SRPLIEKHLA LFFNRSADDG CAMLEPQDVP KNRIGVSAKE
     MILFFGLPND NIMCCDPYSD DLYFMAPPLE DLSSQDYKRS TMESLIACAT PENNLYLASH
     LSKHFWLYNP VLNSWQELAE RPLGRIHSGM CYLNGHVYLL GGRNPVTDAR LKEVECYSIQ
     RNQWTFVAPL PHSLGKMQVV ALNDHLYVVN KRRMLCYDTK RNRWRHCGSL RRDKLHKACV
     FQDQIICVCD TPVVKAYSPL RGEWKRLGDI PIDSRALNYQ VIQHNNKLLL LTQTLLQHNK
     NRVLIHEYDP ARDTWKSIMA VYVSTLGPVC VSTRVYPACL SSAHSFSTEE DDDSGSSADW
     DLDGLTDADS DSGSSSSFSD ENW
//