ID A0A3P8V718_CYNSE Unreviewed; 391 AA.
AC A0A3P8V718;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=ADP ribosylation factor like GTPase 13B {ECO:0000313|Ensembl:ENSCSEP00000008205.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000008205.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000008205.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000008205.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008323206.1; XM_008324984.2.
DR AlphaFoldDB; A0A3P8V718; -.
DR Ensembl; ENSCSET00000008290.1; ENSCSEP00000008205.1; ENSCSEG00000005258.1.
DR GeneID; 103389541; -.
DR CTD; 200894; -.
DR GeneTree; ENSGT00940000156365; -.
DR OMA; QKMEHEQ; -.
DR OrthoDB; 5483033at2759; -.
DR Proteomes; UP000265120; Chromosome 14.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd04161; Arl2l1_Arl13_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR46090; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B; 1.
DR PANTHER; PTHR46090:SF4; ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00328; SAR1GTPBP.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT REGION 228..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..249
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..366
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 44004 MW; A2828B27F1EF9B63 CRC64;
MFSLMANCCN WLKRWREPAR KVTLVMVGLD NAGKTATVRG IQGENPDDVA PTVGFSKVDL
KQGKFEVTIF DLGGGKRIRG IWKNYYSESH GVVFVVDSSD IQRLQETRET MAEVLQHPRI
AGKPVLVLAN KQDQEGALAE ADIIENLSLE KLVNENKCLC QIEPCSAVLG YGKKVDKSIK
KGLNWLLSNI AKDYEVIAER VQKDTAEQRA LEEQDKKERA ERVRRIREER ERQEREAERE
GRPVPEEEPD DETILSPFQP ISNVISENEN KEKGQNELQE VRTNGPIPDV DHELDEEYEE
EELDDSRQIP ENASSASVAS TTSVEPNKKK MLKLHLKRKH RVDPLRIDDG PTDIPAPPPP
PVGWATPKVS RLPKLEPLGD SKHSASGNVT T
//
