ID A0A3P8V7K3_CYNSE Unreviewed; 944 AA.
AC A0A3P8V7K3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Liprin-beta-1 {ECO:0000313|Ensembl:ENSCSEP00000009181.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000009181.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000009181.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000009181.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-beta subfamily.
CC {ECO:0000256|ARBA:ARBA00007547}.
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DR RefSeq; XP_008310213.1; XM_008311991.2.
DR AlphaFoldDB; A0A3P8V7K3; -.
DR STRING; 244447.ENSCSEP00000009181; -.
DR Ensembl; ENSCSET00000009289.1; ENSCSEP00000009181.1; ENSCSEG00000005894.1.
DR GeneID; 103380157; -.
DR CTD; 561961; -.
DR GeneTree; ENSGT01050000244951; -.
DR InParanoid; A0A3P8V7K3; -.
DR OMA; VETQPCD; -.
DR OrthoDB; 5396517at2759; -.
DR Proteomes; UP000265120; Chromosome 6.
DR CDD; cd09563; SAM_liprin-beta1_2_repeat1; 1.
DR CDD; cd09566; SAM_liprin-beta1_2_repeat2; 1.
DR CDD; cd09569; SAM_liprin-beta1_2_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037617; Liprin-beta_SAM_rpt_1.
DR InterPro; IPR037618; Liprin-beta_SAM_rpt_2.
DR InterPro; IPR037619; Liprin-beta_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF16; LIPRIN-BETA-1; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 587..651
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 664..722
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 346..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 163..310
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 346..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 944 AA; 106960 MW; 4E1A70EDE09E9051 CRC64;
MMSDASDMLA AALEQMDGII AGSKALDYSN GLYDCQSPTS PFMGNLRALH LLEDLRSVLE
LMDTEERETL RCQIPDSTAD SLVEWLHGQL SNGHISLSSG DHYQERLSRL ESDKESLVLQ
VSVLTDQVEA QGEKIRDLDL CLDEHREKLN TTEEMLQQEL LCRAALETQK LELMSELTNL
KLKLNNFDKE RVDFDDRFRD SEDLILEINE LRYRLTDMES EKILYEKKLK STMEELAALR
RQLEGKDGDV RRLQDETGFK VMALSSGDSS ERDVEVQRMK KAVESLMEAN EEKDRKIEEL
KQSLQRYKKV QDMVMSVQGK KEKFKENEHV ESQADAPSAI LSASEELEKH EVTDVQQLKR
RSPDELEILN GPYVNSSPSP SPSDLGQVFE STPADVKSSQ DITKTNSQEH LDINNEMSKS
EEVSKKKEKP PLNPAATSTS ATDDAPFGSG KARSSFGKGF FKIRGGKKTG SSPNLDRSRS
ASAPMLAETE QRGTDHLDLA GLPQRSSNSD STHTLPTTPE NAKKSRGIKK LFGKLKRSQS
TTFNLDDNLP PAEFKRGGVR ATAGPRLGWS RDLQRVHTDI DAPFARWSKD QVCDWLQEQG
LGLYVNMARI WISSGQTLLQ ASQHDLEREL GIKHSLHRKK LQLSLQAIGS EEEDNKGKLD
YHWVTRWLDD IGLPQYKTQF DEGRVDGHML HYMTVDDLLS LKVGSVLHHL SIKRAIQVLR
LNNYEPNCLR RRPSDENSTP AEISQWTNHR VMEWLRSVDL AEYAPNLRGS GVHGGLMVLE
PRFNVEAMAL LLNIPPNKTL LRRHLATHFN LLIGSEAQQL KQECLENPDY VLLTAATKVK
PKKLSFGSFG TLRKKRQDEN EEYVCPMDVE MPKSRSFQKD YELQIYEDDL DRLKQMEDSE
GTVRQIGAFS EGIQNLTSML KDDEFFKEIS NSPNSSVTDE DSNA
//
