ID A0A3P8VE46_CYNSE Unreviewed; 2144 AA.
AC A0A3P8VE46;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSEP00000012657.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000012657.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000012657.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000012657.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSCSET00000012809.1; ENSCSEP00000012657.1; ENSCSEG00000008065.1.
DR GeneTree; ENSGT00940000163982; -.
DR OMA; TIFADHT; -.
DR Proteomes; UP000265120; Chromosome 6.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039497; CC144C-like_CC_dom.
DR InterPro; IPR021885; DUF3496.
DR PANTHER; PTHR24147; ANKYRIN REPEAT DOMAIN 36-RELATED; 1.
DR PANTHER; PTHR24147:SF53; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26 ISOFORM X1; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF14915; CCDC144C; 1.
DR Pfam; PF12001; DUF3496; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..2144
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018065917"
FT REPEAT 21..53
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1256..1558
FT /note="CCDC144C-like coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF14915"
FT DOMAIN 1955..2039
FT /note="DUF3496"
FT /evidence="ECO:0000259|Pfam:PF12001"
FT REGION 78..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..1036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1379..1415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1803..1822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1864..1890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1059..1205
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1734..1803
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1948..1975
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 81..99
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..293
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..475
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..491
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..607
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..786
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..1003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1379..1393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1394..1415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1876..1890
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2144 AA; 241692 MW; D4872172183BF301 CRC64;
MNAILLPVFC HFTLCFHPNL IPRSPLMIAA SNGQIGMLRL LLRFNADVTL KDTKGWSADD
YAVMNGHHPC SLLIIEHGTQ RSGGPSHSHQ GQNKKKKVSM TGSPYHDVEA GFSLGGPATD
KDEHGANEAG GDAEDISQSE SLSRVSKSAS DEWPSSEEDE EEELVLSKKK PQKVNLRKMI
ATKKGEASAL LDQSLSGTES DLENDTRIQR IPSLHHQSLH SRNVLQQPVE PAPISFISKA
PQKTFNPQEK EDSTGEEEEE EEDDDEEEED DDDDNEQVGD DEEEDEEEDD QPAQIEKLPD
ATTTVPVTEV TKDRRRDFLS ELGLQKEEEE HSSWDSESHS ENPDMLEEKP NMATQKEEEE
EGGSAAQQVT KETEHKDDVV EHNADDDTAQ REVEKPKWEK LGLLNRLEEN NDRKTDLMEE
LGLGDVDDLE DASDWDSAST TSRRTLPGRK IASPIHDEIP ESPDPTNKEP DEDVTPVTPQ
RSNNSDISSS PQPLPHPQPR ARRLVLQKSE SEDESDWKHE NLGSESTTDK TDNRLKPAAD
IQTMNKPDSS ELSSVARNGQ THREADNGRY KEGHETEDSC EVDPNSQSPS SLMNSDRPEV
NDFSDQPSVE ETVRDSGDVP WEKRYEKLWV EVEKRDVKST FKNVAGELKE RFGELLKSRC
SAEEEQTTAE QNSAEESSSE DEEGEVIVRP TARARRTVLL PIPEQRESGQ EESVTESPEN
SLCEDPMSKE GSTHRPIPGL PYSDHLEECG SPSPHLHADL DFTVQPASDD DGGSVIEEEE
FESIPQQQTD SEEKTPDQQM EETSADSSEE AREKAKESSH LVSDQELKEE VERFKPQVGM
LTKVCLDLEK EKIQLKREVG EEVTEPLAEV HKASASWDAG KETLKEVGTG KPESSSKCVS
GSSGAVHQDL QSAGAQSPNG TTVLSHLPLQ QSNSSNNNKK NGLTVEETTK TEVVRGARHG
RAPQTNTHVN GDPLSVFDDS TLSDVSDNEG MNEGQGRLPS SGQPKNEKQD EMEMTEDFDE
LTQSSDTATD EIDSPTSGYR HASILIQKLD SATLDSSTMV KLQNIFHEYE RSIQKARSRH
GSLADKVCQL ELERAELNIV LDEVKDVKSA LERNQLELQT EVTNLRFQLK QEQENRRNAT
MMYNNTKDKL RKIEDQHQLE VQERQKVELT YRNLELEMRT LVANIKQLEE DHSETQRLLA
QERSARTLQE NLLNGHLRKQ QEIEEENKRN VFKSNEALSQ LTEATDRERE LLRQTATLQE
QLTILRADLQ SSQANSGLKE SQILEENEAL KEQLEDARRD LKLNSDALTQ TVFSSNNQVT
ALKSELAMMT TRLENERQSR ETLEVEVEST RTRLAGAVNE AERCLAAQAS AEKALLREKE
DHQRLKDKLS GEAASQRETV SSLSQKLAKT EASANSMENE VHRVSLQLTE KGLLLEVLQR
EKDQALARVK ELETALNAER EQVSRAKARQ EASQERLAQN QSEVMLLRQQ LEESQNKGDA
KERAVTDAQE RFSDILSKLR SDSEERVQMV EERNKELSSK AADLRDQIYK LEEERNDRET
NLRQLQQELA DSLKKLSMSE ASLEVNTRYR SDLEEEKTRL LKDMDRLKGK LEDSEDQYLQ
AEKRFNGLKS SLDEKDKELD TTAQKLQEAL SASAASGTTI KQLEDAVQKL EIENARLEAA
AKQQSNKIDA LQKGAHEAAM LSDFSPGGGV QRQNALSHTA QDSQALWEDE LKSRSKLGLR
MAELEKERGE LNTQVEIEKK KFKKMAEQKK AVDTRLDQEM NRNTELQKEM YRLRTLLKTA
KKKLRDQNSA GGSPMSTMQM DFGRNSQADG GLGRMREKLD DLQMQLQREV SRCGQLEQTN
RELKDQLAQK SYSHSSDQLE RSKRQLEEEV SDLRRRMETA QMEQGQAEQF RRDVEEKARQ
EIQRKLDQVN LFLQSQAASQ EALDQIRAAN ESNVRSQLEQ KIRELEAALL QTRTTQQESL
IQRDSTRTEL DRYRELYSEE LRLRKSLSAK LDRSNTRLAE ANSKLLNERS RSFITSSIAN
GSLVNPSLDV GALVSPGVTL NRSLGLGVLS PGSEGQNSRV EDYLAKMQSE LDKNISKELN
TATAELDIAT MRLSPVGSAS RVDLDPVSRA TQQYLEVLKR NNMI
//
