ID A0A3P8VE97_CYNSE Unreviewed; 708 AA.
AC A0A3P8VE97;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=F-box only protein 40-like {ECO:0000313|Ensembl:ENSCSEP00000013623.1};
GN Name=FBXO40 {ECO:0000313|Ensembl:ENSCSEP00000013623.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000013623.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000013623.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000013623.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8VE97; -.
DR STRING; 244447.ENSCSEP00000013623; -.
DR Ensembl; ENSCSET00000013782.1; ENSCSEP00000013623.1; ENSCSEG00000008742.1.
DR GeneTree; ENSGT00950000183204; -.
DR InParanoid; A0A3P8VE97; -.
DR Proteomes; UP000265120; Chromosome 19.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 3.30.40.150; TRAF-like zinc-finger, N-terminal subdomain; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR031890; Fbxo30/Fbxo40.
DR InterPro; IPR001293; Znf_TRAF.
DR InterPro; IPR043013; Znf_TRAF_N.
DR PANTHER; PTHR15933; PROTEIN CBG16327; 1.
DR PANTHER; PTHR15933:SF21; ZGC:172158 PROTEIN; 1.
DR Pfam; PF15966; F-box_4; 1.
DR Pfam; PF15965; zf-TRAF_2; 1.
DR SMART; SM00256; FBOX; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 54..96
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 567..621
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT ZN_FING 54..96
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 221..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..268
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 80731 MW; 686CB4809B8D0EA8 CRC64;
SSRHRCSRGR QHLHCDSCYS RRCRTRVEAS VSCALVPCGL LCGAVFHLCK EEEHLLLCPN
VRVPCLNADH GCPLQMPRSC RAAHLQECPA SVVCCSMDWL RWPVDETNPH GNVALQENVQ
KEHEGQQEAL DLAMARVDQC ELYQRLEMEP LYPELMEEQE EEEKTGPRET VVSCVSTGSS
SCRSYVEETV QPRHQVVIDK DKFNLFEMMF SMDRRACEVA QENLERSKSE ETVRTERRDD
AQDAGRSEVR EKGVDHQETD DKTLRPPEPQ PDTSKTGQAP WQEGVMERLK EELTPQEYNM
YVVHHGRMLM AFGQIQACTP REKDFVYGSL EPIPVQTLRS FKVPDSYHYR RRVHLYDTAA
RAPREPRGVD TSDLGSSEDL WFSEEDTSTL LGYAEREVMG HKISESKAAD GLYVDVGTQT
HRFHSAPLSR RTTLAQVMEV KPQRLLLQLQ TESVTGRHSR ATCVFSFLCG HTFHRREFAT
HFRNVHGEIQ TCLSGWFEQR CPLSYLGCTY SRRRFQPASH RASVYYDFNL RPTLGAPSGD
DFRRNLFDSS TNQREQGAGV EGAGGGADSL SSLPYEVLCH VASFLDSLSL SQLALVSRLL
RQVCSSLLQD RGMVTLHWEK DTSSHGGAKR WRSRPVWRFS HLFSSVDSWR TSDVPPMSAH
LKVCPFYQTS EEQQQSRRVP LPGMSEKLRS SQKGATLVDL LTRNRQHQ
//
