ID A0A3P8VF90_CYNSE Unreviewed; 934 AA.
AC A0A3P8VF90;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ADAMTS-like 2 {ECO:0000313|Ensembl:ENSCSEP00000013973.1};
GN Name=ADAMTSL2 {ECO:0000313|Ensembl:ENSCSEP00000013973.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000013973.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000013973.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000013973.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 244447.ENSCSEP00000013973; -.
DR Ensembl; ENSCSET00000014137.1; ENSCSEP00000013973.1; ENSCSEG00000008963.1.
DR GeneTree; ENSGT00940000159447; -.
DR InParanoid; A0A3P8VF90; -.
DR OMA; CGEGHQF; -.
DR Proteomes; UP000265120; Chromosome Z.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 5.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF281; NO LONG NERVE CORD, ISOFORM C; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF08686; PLAC; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 4.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00209; TSP1; 7.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS50092; TSP1; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 892..930
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT REGION 358..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 52..93
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 56..98
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 67..83
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 934 AA; 103859 MW; 3B435090F5D96B7B CRC64;
GVERRVWSLI ECVSVLRVCV CVKEEGVAFN SLEEELEVTT YWWGEWAKWT ACTRTCGGGV
MSQERHCLKQ RKKVAAGKDN MTCTGTAKKY HLCNTRECPA PGRSFREEQC WSFNSQLYNG
RNFQWKPLYP DDYVHISSNP CDLHCTTTDG QRQLMVTARD GTSCKYSSYH GVCVDGKCEP
IGCDGVLFSS NTLDKCGVCQ GDGSSCSRVT GNFRRGAMTL GYSFITQIPE GSWDIQIIER
KKSADVLAVT DQAGNFFFNG AYKVDSPQNF HAAGTVFKYR RPMDVYETGI EYIVAKGPID
QAINILVWNQ NGRIPYITYE YTVLRDSLPP IPPPPVYTGA DSSAAEVSVE VGGLLPSNAS
VHRQTGPQSV QGEVGADGQK GQETNEVYEE SAAIDCEQDS PKYTGEDHET SLLNVDIVLR
LKGDCLFFTY YINILFIHSQ LSSAASIRQT ETAVVPAXXX XXXXXXXXXX XXXXXXXXXX
LNGRLNPDDL LINISTNQLL TEGAALFSSE AGPPDVELSS LDQEADLNDT LELNQKNQKM
SAADMYRWKL SSQEPCSMTC SIGVSRSFVS CVRYDGVEVH DMYCDALTRP EPVHDFCIGR
ECQPRWEASS WSECSRTCGE GFQFRQVRCW KMLSPGLDSS VYSDLCTIAD LERPVERRAC
KSPACGPQWE VAEWSECPAK CGQKAQVSRD VRCSDETRLC DLMTKPPTVK NCTGPPCERH
WTVSEWGPCS GSCGQGKMLR HVYCKAPDGR VVPENQCPVE NKPLAIHPCG ERDCAPHWLS
QDWERCNTTC GRGMKSRTVM CVGISAGKFQ TFDDDACGGS EKPEEDDTCF ERPCFKWYTT
PWSECTKTCG VGVRMRDVKC YQGRELVRGC DPLTKPVAKQ TCTLQACPTE PPDESCQDRP
SANCLLALKV NLCSHWYYSK ACCHSCRAVR PPPS
//
