ID A0A3P8VJX8_CYNSE Unreviewed; 964 AA.
AC A0A3P8VJX8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=PHD finger protein 20 {ECO:0000313|Ensembl:ENSCSEP00000014647.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000014647.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000014647.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000014647.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008318753.1; XM_008320531.2.
DR AlphaFoldDB; A0A3P8VJX8; -.
DR Ensembl; ENSCSET00000014825.1; ENSCSEP00000014647.1; ENSCSEG00000009421.1.
DR GeneID; 103386326; -.
DR CTD; 563332; -.
DR GeneTree; ENSGT00940000156477; -.
DR OrthoDB; 5491784at2759; -.
DR Proteomes; UP000265120; Chromosome 11.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20104; MBT_PHF20L1-like; 1.
DR CDD; cd20453; Tudor_PHF20; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR041297; Crb2_Tudor.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR043449; PHF20-like.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR15856:SF27; PHD FINGER PROTEIN 20; 1.
DR PANTHER; PTHR15856; PHD FINGER PROTEIN 20-RELATED; 1.
DR Pfam; PF02820; MBT; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF18115; Tudor_3; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 388..418
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 164..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 416..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..186
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 964 AA; 110886 MW; 35254218871840D8 CRC64;
MQRRRRDRMS ASPVQNNRDE ENSLDVSSMS KVPPNRRGIT FEVGAQLEAR DSLKNWYAAN
IEKIDYEDEK VLIHYRQWSH RYDEWFDWTS PYLRPVDKIQ LRRQGLQGDS CVPGFHVNEK
VLASWSDCRF YPAKVISVNK DASYTVRFYD GVIQTVKGMH VKPFIKERNR SSKSRSSERN
MVRRAPNRRD GGLNGGPKNK RARPSASDQE EESDSEDEEH KEQLVIQNQT KKSDGTVEAS
SAIKQEKEMM EQGDENHSRE TENGTKLKNE ENVKDEKHND KCHVNGDVKK EPQDLEEEGK
KPYMESTKPY MESTAQTSAE TKLMSNGALE PKSESAQPTT DVPPSQLVKP VRKQGFHNPN
RFSREPLYRV IKNQPPPVLS INLDHNPFKC SAPGCTKSFR KAKLLHYHMK YYHGEETPLE
EEHSPSRNIQ NRVSEKQTMA TGLDVPKRRR TISASIHSVA GGHYSQGDVK TSGRRTSVPP
AGGTQNHQHR TLLREKSKEN QLDRNRCHQE DRSSEKSGFD IGSVKDKLKE KPKQKDFLRI
KLKKRKKRKK AKSDEDSFSD WSTDSCGWSD DDMGVDLDVT TPPLSVDSCA ADISDQEVVR
CICGVEEEND FMIQCEDCLC WQHGTCMGLL EENVPDKYTC YICRDPPGQR QSLRYWYDRE
WLTNGHMYGL SFLKENYSHQ NAKKITTTHQ LLGDVQHVLE IINGLQLKMN VLQSNFHPDL
QLWRQPWKHL RSLPSSDSHQ GSDKAPLPVV PDEEMSRGEM LMSNALEKLS RAATAANTSS
LLSCSPSPFP SFQDSYISSE HCYQKPRAYY PAVEQRLVVE TWQGSELEDS MRSTEELLER
EQRYGSLLET DKPKSTVNGN KVTLANLWSQ SDMKDVVRRE PGAADKNRQH QQWQINLLDH
IDAVQDDVSH RMDFIERELD VLESWLDYTG ELEPPEPLAR LPQLKHRIKR LLSQLDIMQQ
ISSM
//
