ID A0A3P8VKC1_CYNSE Unreviewed; 423 AA.
AC A0A3P8VKC1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Saccharopine dehydrogenase-like oxidoreductase {ECO:0000256|ARBA:ARBA00039852};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000012890.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000012890.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000012890.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00038048}.
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DR RefSeq; XP_008308616.1; XM_008310394.2.
DR AlphaFoldDB; A0A3P8VKC1; -.
DR STRING; 244447.ENSCSEP00000012890; -.
DR Ensembl; ENSCSET00000013046.1; ENSCSEP00000012890.1; ENSCSEG00000008331.1.
DR GeneID; 103379003; -.
DR KEGG; csem:103379003; -.
DR CTD; 51097; -.
DR GeneTree; ENSGT00390000004799; -.
DR InParanoid; A0A3P8VKC1; -.
DR OMA; MQLRYHD; -.
DR OrthoDB; 5479972at2759; -.
DR Proteomes; UP000265120; Chromosome 5.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 11..148
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
SQ SEQUENCE 423 AA; 46017 MW; 67F994818AE3CEAF CRC64;
MSSSSRPYHL VIFGASGFTG QFVVEEVART ISEGPGGTLK WAVAGRSKQK LEKVVGQAAE
ILGKPELRSE VDIIIADVGQ PDSLASMCRQ AVIVLNCVGP YRFYGEPVVK ACVENGAHHI
DISGEPQFLE AMQLNYNSQA ADAGVYVIGS CGFDSIPADM GVIYTREQFK GTLTAVESFL
TIGSGPDGVC IHDGTWQSAV YGFADSNNLQ SLRRKFQHKP LTYVGSRLRR RGNLFFSSEI
QQYSLPFMGS DPSVVKRTQR YLAEEHHQTP VQYGAYAGVG GISNVIKLMF AGMMFWFLVK
FSFGRNLLIK FPEFFSFGVF SKAGPSKKQM EASSFQFAFL GEGYTEGLDP SQGKPNGKIR
ILVQGPECGY VATPIAMVQA ALTILHEPAA LPKRGGVYSP GAAFAKTSLI ERLNKHGIQF
SVI
//
