ID A0A3P8VKQ8_CYNSE Unreviewed; 300 AA.
AC A0A3P8VKQ8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Protein FAM49A-like {ECO:0000313|Ensembl:ENSCSEP00000014869.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000014869.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000014869.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000014869.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CYRI family.
CC {ECO:0000256|ARBA:ARBA00005778}.
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DR AlphaFoldDB; A0A3P8VKQ8; -.
DR Ensembl; ENSCSET00000015045.1; ENSCSEP00000014869.1; ENSCSEG00000009533.1.
DR GeneTree; ENSGT00390000015159; -.
DR Proteomes; UP000265120; Chromosome 18.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro.
DR InterPro; IPR039789; CYRI.
DR InterPro; IPR009828; CYRIA/CYRIB_Rac1-bd.
DR PANTHER; PTHR12422:SF2; DUF1394 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12422; UNCHARACTERIZED; 1.
DR Pfam; PF07159; CYRIA-B_Rac1-bd; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 19..211
FT /note="CYRIA/CYRIB Rac1 binding"
FT /evidence="ECO:0000259|Pfam:PF07159"
SQ SEQUENCE 300 AA; 34153 MW; 58E2AEF1FB44CAE9 CRC64;
MGNLLKVLAC AELEHGPIVF LDFEHAQPTE AETAVWNQVS AVLEEAHGIL AELQSYNGAG
QEIREAIQNP GDLALQEKAW NAVCPLVAKL KRFYEFSLRL ENALRSLLEA LTSPPYAPMQ
HLEREQALAK QFAEILHFTL SFDELKMTNP AIQNDFSYYR RTISRNRLNN QQLEAENEVN
NEMANRMSLF YAEATPMLKT LSNATTKFVS EVLLRLSPPS SPVRSSTHFG GRFTIMEKTF
CHQFPSVTIC QFRRSRNFPT SHLSAFSTEQ KSRKDFRGVH KQFRGHVGSE MLFSKVTLRP
//
