ID A0A3P8VL66_CYNSE Unreviewed; 1877 AA.
AC A0A3P8VL66;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Myosin-10-like {ECO:0000313|Ensembl:ENSCSEP00000013195.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000013195.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000013195.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000013195.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR Ensembl; ENSCSET00000013354.1; ENSCSEP00000013195.1; ENSCSEG00000008381.1.
DR GeneTree; ENSGT00940000155159; -.
DR OMA; ENREHRS; -.
DR Proteomes; UP000265120; Chromosome 9.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF24; MYOSIN-10; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 1.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 31..81
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 85..825
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 200..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..725
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 973..995
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1735..1771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1811..1837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1735..1759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1811..1829
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 178..185
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1877 AA; 218326 MW; 29BB6199754FAC21 CRC64;
MSQRSGQEDP ERYLFVDRAV VYNPAAQADW TAKRLVWVPS ERHGFEAASV REERGDEVVV
ELAENGKKAM VNKDDIQKMN PPKFSKVEDM AELTCLNEAS VLYNLKDRYY SGLIYTYSGL
FCVVINPYKN LPIYSENIIE MYRGKKRHEM PPHIYAISES AYRCMLQDRE DQSILCTGES
GAGKTENTKK VIQYLAHVAS SHKGKKDHNV PPESPKPAKL QAQNSVSGPL FYGELERQLL
QANPILESFG NAKTVKNDNS SRFGKFIRIN FDVTGYIVGA NIETYLLEKS RAIRQAKDER
TFHIFYQLLA GAGEHLRSDL LLEGFNKYRF LSNGNIPIPG QQDKDNFHET MEAMHIMSFA
HEEILAMLKV VSAVLQFGNV IFKKERNTDQ ASMPDNTAAQ KLCHLLGMNV MEFTRAILSP
RIKVGRDYVQ KAQTKEQADF AVEALAKATY ERLFRWLVHR INKALDRTKR QGASFIGILD
IAGFEIFQLN SFEQLCINYT NEKLQQLFNH TTFILEQEEY QWEGIAWSFI DFGLDLQPCI
DLIERPANPP GVLALLDEEC WFPKATDKTF VEKLIQEQGT HTKFQKPRQL KDKADFCIIH
YAGKVDYKAD EWLMKNMDPL NDNVATLLHQ STDKFVAELW KDDIQTIQRA SFYENVTSLD
EPAVDRIVGL DQVAGMNETA FGATYKTKKG MFRTVGQLYK ESLTKLMATL RNTNPSFVRC
IIPNHEKRAG KLEPHLVLDQ LRCNGVLEGI RICRQGFPNR IVFQEFRQRY EILTPNAIPK
GFMDGKQACE RMIRALELDP NLYRIGQSKI FFRTGVLAHL EEERDLKISD IIIYFQSVCR
GYLARKAFAK KQQQLSALKV LQRNCAAYLK LRHWQWWRLF TKVKPLLQVT RQEEELQAKD
EELVKVKERQ LKVENELVEM ERKHQQLLEE KNILAEQLHA ETELFAEAEE MRVRLLSRKQ
ELEEILHDLE SRVEEEEERN QSLQNEKKKM QSHIQDLEEQ LDEEEAARQK LQLDKVTAEA
KIKKMEEDIL LLEDQNSKFL KEKKMLEDRV GEMTSQLTEE EEKAKNLSKV KNKQEMMMTD
LEERLKKEEK TRQELEKAKR KLDAETSDLQ DQIVELQVQV EELKIQLTKK EEELQTALAR
GDEEAIQKNN TLKQVRELQA QLVELQEDLE SERICRSKAE KLRRDLSEEL EALKTELEDT
LDTTAAQQEL RTKREQEVAE LKKAIDEETK NHEAQVQEMR QRHATALEEL SEQLEQAKRF
KTNLEKNKQC LESDNRELSC EIKNLQQTKT ESEHKRKKVE AQLQEFMTKT TEVERVKGEL
ADRSNKLQVE LDNVSVLLEE AEKKGVKLTK EVENLNSKLQ DSEELRQEET RQKLNLSGQI
RQLEVEKNTL LEQQEEDEEA RRNLEKQLQS VQAQLFEAKK KLEDDVGAME GLEEAKRKLQ
KDMELTSQRL EEKTMSMDKM EKTKNRLQQE LDDLMVDLDH QRQIVSNLEK KQKKFDQMLA
EEKTISARYA EERDRAEAEA REKDTKALSM ARALEEALEA KEELERFNKQ LRVEMEDLMS
SKDDVGKNVH ELEKSKRMLE QQVEEMRTQL EELEDELQAT EDGKLRLEVN MQAMKAQFDR
DVQARDEQGE EKKRALVKQV REMEAELEDE RKQRAMSIAA KKKLEMDLNE LEGQIEAATK
GRDEAVKQLK KLQAQMKDYQ RELEEARASR DEIFTQSKEN EKKLKSLEAE ILQLQEDHAA
SERARRHAEQ ERDELADEIS NSVSGKSSLL EEKRRLEARI SQLEEELEEE QGNMEMINDR
LRKTTLQVEG LTTELSGERS TAQKSENARQ QMERQNKDLK AKLAELEGAV KSKFKASIAA
QEAKILQMEE QLEQEVK
//
