ID A0A3P8VMD2_CYNSE Unreviewed; 376 AA.
AC A0A3P8VMD2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Kelch domain-containing protein 10 {ECO:0000256|ARBA:ARBA00041041};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000014396.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000014396.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000014396.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the KLHDC10 family.
CC {ECO:0000256|ARBA:ARBA00038487}.
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DR AlphaFoldDB; A0A3P8VMD2; -.
DR Ensembl; ENSCSET00000014566.1; ENSCSEP00000014396.1; ENSCSEG00000009250.1.
DR GeneTree; ENSGT00940000155977; -.
DR OMA; IHKHYLY; -.
DR Proteomes; UP000265120; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR46428; KELCH DOMAIN-CONTAINING PROTEIN 10; 1.
DR PANTHER; PTHR46428:SF1; KELCH DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF13854; Kelch_5; 1.
DR Pfam; PF13964; Kelch_6; 2.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 3: Inferred from homology;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 141..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 376 AA; 42754 MW; B7707A1F343F63FF CRC64;
MYVKRSVSFY NSNFDPSSGH RTPPARSGHR CVADNTNLYV FGGYNPDYDE SGGSDNEDYP
LFRELWKYHF ATGCWQQIRT EGYMPTELAS MSAVLHGNNL LVFGGTGIPF GENNGNDVHV
CNVKYKRWSL LNCRGKKPSR IYGQAMVIIN GFLYVFGGTT GYIYSTDLHR LDLTAREWIH
LKPNNPRDDL PEERYRHEIA HDGQRIYILG GGTSWTSYPL DKVHAYNLET NSWEEITTKP
HGKTGHPAPR RCHSCVQIRN DVFICGGYNG EVILADLWKL NLQTFQWSKL PAVMPEPAYF
HCAAVTPAGC MYIHGGVVDI HENKRTGSLF KIWLVVPSLL ELCWEKLLKA FPHMSSLPNL
ELLNLGLTQE LIHRLK
//
