ID   A0A3P8VQQ2_CYNSE        Unreviewed;       435 AA.
AC   A0A3P8VQQ2;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Major facilitator superfamily domain containing 11 {ECO:0000313|Ensembl:ENSCSEP00000016609.1};
OS   Cynoglossus semilaevis (Tongue sole).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC   Cynoglossinae; Cynoglossus.
OX   NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000016609.1, ECO:0000313|Proteomes:UP000265120};
RN   [1] {ECO:0000313|Ensembl:ENSCSEP00000016609.1, ECO:0000313|Proteomes:UP000265120}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24487278;
RA   Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA   Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA   Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA   Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA   Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA   Zhao Y., Schartl M., Tang Q., Wang J.;
RT   "Whole-genome sequence of a flatfish provides insights into ZW sex
RT   chromosome evolution and adaptation to a benthic lifestyle.";
RL   Nat. Genet. 46:253-260(2014).
RN   [2] {ECO:0000313|Ensembl:ENSCSEP00000016609.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the unc-93 family.
CC       {ECO:0000256|ARBA:ARBA00009172}.
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DR   AlphaFoldDB; A0A3P8VQQ2; -.
DR   Ensembl; ENSCSET00000016821.1; ENSCSEP00000016609.1; ENSCSEG00000010628.1.
DR   GeneTree; ENSGT00390000012918; -.
DR   OMA; QFQDKTH; -.
DR   Proteomes; UP000265120; Chromosome 17.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd17407; MFS_MFSD11; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR010291; Ion_channel_UNC-93.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR23294; ET TRANSLATION PRODUCT-RELATED; 1.
DR   PANTHER; PTHR23294:SF28; UNC93-LIKE PROTEIN MFSD11 ISOFORM X1; 1.
DR   Pfam; PF05978; UNC-93; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        263..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        331..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        371..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        397..418
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   435 AA;  47398 MW;  2E9C263B41EE822C CRC64;
     MSPESKKQMN IIILGVSFMF MFTAFQTCGN IEQTVIKSFN SSDMSIIYAV MSTSNVLAPS
     VVAVIGPQLS MFFSGLLYSG YIAMFIYPYT WTFYTASVLV GIGAAVLWTA QGNVLTINST
     NNTIGRNSGI FWSLLQFSML FGNLYIYFAW HGHVHITDKD RRTVFISLTV ISLVGCFLFF
     LIRTPETESA PSEVSESLLE AEFSESTTTR SDGKPVCKIT VTKEMLLLFL PLAYSGLELT
     FYSGVYGTCI GAMTGFGQDA KSLIGISGIF IGVGEILGGG IFGLLNKNNR FGRNPVVLLG
     LITHFVAFYL IFLNIASDAP LAPEAGTDKQ AFITPNVGVA MLCSFLLGLG DSCFNTQLMS
     IIGFMFPDNS APAFASLKLI QCVAAAIAFF YSNFLLLHWQ LLILVLTGFL GTITFFAAET
     LAESNRRESS DYGTI
//