ID A0A3P8VX11_CYNSE Unreviewed; 673 AA.
AC A0A3P8VX11;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ribonuclease inhibitor-like {ECO:0000313|Ensembl:ENSCSEP00000018864.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000018864.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000018864.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000018864.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8VX11; -.
DR STRING; 244447.ENSCSEP00000018864; -.
DR Ensembl; ENSCSET00000019098.1; ENSCSEP00000018864.1; ENSCSEG00000012073.1.
DR GeneTree; ENSGT01070000253760; -.
DR InParanoid; A0A3P8VX11; -.
DR OMA; FHYEVIS; -.
DR OrthoDB; 4210789at2759; -.
DR Proteomes; UP000265120; Chromosome 17.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF13516; LRR_6; 5.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM00368; LRR_RI; 11.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 62..122
FT /note="NOD2 winged helix"
FT /evidence="ECO:0000259|Pfam:PF17779"
FT DOMAIN 124..267
FT /note="NACHT LRR and PYD"
FT /evidence="ECO:0000259|Pfam:PF17776"
SQ SEQUENCE 673 AA; 75595 MW; F58E1FCC0EFCDB4C CRC64;
MCQIPVFCWI SATVLEHMLT SEQTGELPRT LTDLYSHFLL VQTKRKKKKY SGGPETGLLD
GDVLLKLGRL AFEHLQKGNI MFYQEDLDQC GLDVTQAMVY SGVCTEIFRR ESVIFKKTVY
CFVHLSVQEF LAAVYMFHCY TNRRTQVLQD FLGKEYKPSK SKLETIVNTF KVKYDFTMTD
FLRKSMEKSL QSKNGHLDLF VRFLHGLCLE SNQRILGDLL GQTHYSPETI PKVIENLKSM
NTINISPERS INIFHCLTEL KDQSVHQQIQ EFLKSKNREK ELSEIQCSAL AYILQMSEEV
LDELDLEKYN TSKEGKLRLI PAVRNCRTAR LVGYDLSETG AEVVASALKS SPSHLIELDL
RNIQLQDAAV DHLCSGLKSP HCGLESLRLS SCSLSKISCS SLVSVLKSNP SHLRKLDLSW
NNLKDSAVKD LCGFLQSPDC KLETLWLSSC RLTEISCSSL VSALKSNPSH LRKLDLSFNN
LKDSAVEDLC GFLQSPDCKL ETLWLSSCRL SEISCSSLVS ALKSNPSRLR DLDLSGNNLK
DSAVKDLCGF LQSPDCKLED LWLNDCRLSE ISCSSLVSAL KSNPSHLRKL YLSYNNLKDS
SVEDLCGFLQ SPDCKLDDLR LSSCSLSEIS CSSLVSALTS NPSHLRKLDL RGNNLEDSAV
EDLRGLVDDL MSV
//
