ID A0A3P8W456_CYNSE Unreviewed; 414 AA.
AC A0A3P8W456;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Serpin B6 {ECO:0000256|ARBA:ARBA00039202};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000020381.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000020381.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000020381.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Forms a complex with the monomeric form of beta-tryptase.
CC {ECO:0000256|ARBA:ARBA00038828}.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR AlphaFoldDB; A0A3P8W456; -.
DR Ensembl; ENSCSET00000020634.1; ENSCSEP00000020381.1; ENSCSEG00000012834.1.
DR GeneTree; ENSGT00940000154835; -.
DR Proteomes; UP000265120; Chromosome 3.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd19956; serpinB; 1.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF204; SERPIN B6; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 17..413
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 414 AA; 46895 MW; F2394D9FFF3DE05D CRC64;
MYLESTPLSE ANTSFCLDLF KQLSDNDKTA NVFFSPFSIS SALAMVMLGA AGNTHTQMSE
VLGFTEAKQQ PPARAQQQQQ QQQQRQQAID LPAYLLKVQC QDVHSDFSQL LSVLNKPGAP
YALSVANRLY GEQSYQFVED FLGLTRKHYN AELEAVDFVG SHEAARVNIN NWVENQTQGK
IKDVLANGVV DNMTRLVLVN AIYFKGNWNK QFEERATRDA QFRINKNDTK PVKMMYQKAK
FPLTYISEVS CQILEIPYKD KDLSMLIFLP SEIEDNSTGL EKLEKALTYE NVMEWTRPDM
MDDVEVQLGL PRFKMEEKYD LKNVLVNMGM VDAFDVAMSM SPSNDLFLSK VVHKAFVEVN
EEGTEAAAAT AAVMMLRSLP RPPPPFIADH PFLFFIRHNA TKSILFAGRY CSPE
//
