ID A0A3P8W4A4_CYNSE Unreviewed; 668 AA.
AC A0A3P8W4A4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Si:ch211-117l17.7 {ECO:0000313|Ensembl:ENSCSEP00000021454.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000021454.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000021454.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000021454.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8W4A4; -.
DR STRING; 244447.ENSCSEP00000021454; -.
DR Ensembl; ENSCSET00000021730.1; ENSCSEP00000021454.1; ENSCSEG00000013690.1.
DR GeneTree; ENSGT00940000166731; -.
DR InParanoid; A0A3P8W4A4; -.
DR OMA; QGPEYVH; -.
DR Proteomes; UP000265120; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR PANTHER; PTHR24373:SF397; TSUKUSHI; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 13.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..668
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018153433"
FT TRANSMEM 637..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..64
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 431..484
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
FT REGION 503..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 75660 MW; B150E105F188AD26 CRC64;
MLCFLFKCPG YLQFVLVLVA LPHFTCDDSS RCPSACVCRA DGAVRCVGDT VTDVPQLLPP
DTYLLELNGT RITVIKERDL MKKDLLLRFS LTYSSLNTIH PQAFHLGPPL RSVRLSYNYL
NTLPDSVFRQ LTTLEQLYLN GNQFEVIGSD QLTGLTNLVA LDLSRNKLTY LDSDVFQGLK
NLTFLNLCRN FLKRLPTTVF NSLTNLQELH IYNNELEVLQ AGLFDQLVNL RELQLYHNKI
TTLAPQVFWS LQKLTVLSLS SNQLTSIPEK SFYNMPRLTK LTIYKNPLLF LPEQLMGNMP
EIQVFYLFST NLTTVPGNLF TNMSGLLELN FHLNEKLKEL PPDLFCCLRN LKKLSLKSNN
LHDLEPQLFS RLPALKLLFL NDNKLRRLPE NIFRGIAGVL TINLSKNLLT TLPGDIFQSN
TALRSLSLSD NPWDCTCNIR VLARWIARHN AVVTDKNYVM CESPLYQMLR RVDSLPDEEF
NVCDVTTYFP SNTDLDKSTQ PLFTSTQNTI PPTTTTTTTT TTTTTTTTTT TTTTTTTTTT
PEITTPEIRP SSKDTQNLNI LTTTSRGSTS PASWTLTTQA EVTSTMSTMS TLHVFYDVLV
IGWGPEFVHH NIHSGWVYVW FLPSDTAWTA SLMFCHVFLL TTGLVFILAS IYVMNLLDKT
MDELNPRH
//
