ID A0A3P8WB57_CYNSE Unreviewed; 159 AA.
AC A0A3P8WB57;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Glucagon family neuropeptides-like {ECO:0000313|Ensembl:ENSCSEP00000021840.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000021840.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000021840.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000021840.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glucagon family.
CC {ECO:0000256|ARBA:ARBA00008369}.
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DR AlphaFoldDB; A0A3P8WB57; -.
DR Ensembl; ENSCSET00000022119.1; ENSCSEP00000021840.1; ENSCSEG00000013922.1.
DR GeneTree; ENSGT00950000183154; -.
DR Proteomes; UP000265120; Chromosome 20.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR Gene3D; 6.10.250.590; -; 1.
DR InterPro; IPR000532; Glucagon_GIP_secretin_VIP.
DR InterPro; IPR046963; VIP/GHRH-like.
DR PANTHER; PTHR11213; GLUCAGON-FAMILY NEUROPEPTIDE; 1.
DR PANTHER; PTHR11213:SF1; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; 1.
DR Pfam; PF00123; Hormone_2; 1.
DR PRINTS; PR00275; GLUCAGON.
DR SMART; SM00070; GLUCA; 1.
DR PROSITE; PS00260; GLUCAGON; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 115..137
FT /note="Glucagon / GIP / secretin / VIP family"
FT /evidence="ECO:0000259|PROSITE:PS00260"
SQ SEQUENCE 159 AA; 18508 MW; F8A9935805CFC5F0 CRC64;
MASSSKATLI LLIYGILMHY SVFCTPIGLS YPKIRLENDA FDEDGNSLND MGFDSDQIAI
RSPASLNDDA YSLYYPPEKR PERHAEEELD RALREILGLF FFYMEDESEP LSKRHSDGIF
TDSYSRYRKQ MAVQKYLAAV LGRRYRQRVR NKGRRLAYL
//
