ID   A0A3P8WFS7_CYNSE        Unreviewed;       823 AA.
AC   A0A3P8WFS7;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   13-FEB-2019, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=BEN domain containing 3 {ECO:0000313|Ensembl:ENSCSEP00000025282.1};
OS   Cynoglossus semilaevis (Tongue sole).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC   Cynoglossinae; Cynoglossus.
OX   NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000025282.1, ECO:0000313|Proteomes:UP000265120};
RN   [1] {ECO:0000313|Ensembl:ENSCSEP00000025282.1, ECO:0000313|Proteomes:UP000265120}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24487278;
RA   Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA   Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA   Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA   Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA   Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA   Zhao Y., Schartl M., Tang Q., Wang J.;
RT   "Whole-genome sequence of a flatfish provides insights into ZW sex
RT   chromosome evolution and adaptation to a benthic lifestyle.";
RL   Nat. Genet. 46:253-260(2014).
RN   [2] {ECO:0000313|Ensembl:ENSCSEP00000025282.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_008315105.1; XM_008316883.2.
DR   RefSeq; XP_008315114.1; XM_008316892.2.
DR   RefSeq; XP_008315121.1; XM_008316899.2.
DR   AlphaFoldDB; A0A3P8WFS7; -.
DR   STRING; 244447.ENSCSEP00000025282; -.
DR   Ensembl; ENSCSET00000025619.1; ENSCSEP00000025282.1; ENSCSEG00000016148.1.
DR   GeneID; 103383660; -.
DR   KEGG; csem:103383660; -.
DR   CTD; 57673; -.
DR   GeneTree; ENSGT00390000010827; -.
DR   InParanoid; A0A3P8WFS7; -.
DR   OMA; TYRFINE; -.
DR   OrthoDB; 2905331at2759; -.
DR   Proteomes; UP000265120; Chromosome 1.
DR   GO; GO:0000792; C:heterochromatin; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000183; P:rDNA heterochromatin formation; IEA:InterPro.
DR   InterPro; IPR018379; BEN_domain.
DR   InterPro; IPR033583; BEND3.
DR   PANTHER; PTHR28665; BEN DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR28665:SF1; BEN DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF10523; BEN; 3.
DR   SMART; SM01025; BEN; 4.
DR   PROSITE; PS51457; BEN; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT   DOMAIN          235..332
FT                   /note="BEN"
FT                   /evidence="ECO:0000259|PROSITE:PS51457"
FT   DOMAIN          542..643
FT                   /note="BEN"
FT                   /evidence="ECO:0000259|PROSITE:PS51457"
FT   DOMAIN          708..809
FT                   /note="BEN"
FT                   /evidence="ECO:0000259|PROSITE:PS51457"
FT   REGION          36..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          361..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..395
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   823 AA;  94930 MW;  A97A6F02A947620C CRC64;
     MNFSEHGDVS CEAMLEKEDE HVWDIKKETE DHVICNQSEE SGGRRPEACG TSKRTSAEVE
     TDASQSTCSK RARVCGDMKR RLIDVSSRHE PLCLTTMGER RECVHETDRV SYKKPLFSIS
     HRISEKRNTP VTPEQQTSHR VANQHNHSSS IFSSESQILE ENVQMEDLLI AASSGQDSST
     INSSLYPLIE KMFFILNTLS SSMTQLHSKV DQLTLEVMRI KRQVKTSELV TEFQPPPEYL
     LTSDELNQLM EQTSNAGELG CRLLVHLFPE LFKARECSHK CTASKRVLES LHLQLIRNYV
     EVCYPVVKSN SIWQEECLLQ IIDFFNRFWT QRDVESSQSL RKQTLTGAAI KTEHPHTFHF
     INEQRKEEQV TSDTQPSRLP SATDTDFSTQ VSDEVDDFSS PEDSIVFLMH QLFPEVFEGG
     RMADSSNSLS RAGQLILDPD KIDIIRRYME ANFPDVPKDS WLQVCIQHIE DAFEGSHSNG
     NESVLDDINN DGSDLASLSE DVSPSKEPEL MDYERRNRKS KKSLLPPVDF DSLDIPLPDF
     HISQEYLLSR EQLKNNYDCS LSIGNFASRL LVLMFPELFT HENIRKQYNC SGSLGKKQLD
     PVRVNLIRHY VQLVYPQAKN NRVWMLEFVG KLDERCRRRD TEQRRSYLQQ RKVYGPESEQ
     DLFCQLTQLN PDVREDLDIP SLPPEKSSKD FCRIPLDELT VCKPDFPVPS VYLLSDNEVR
     EIVQQSLSVG NFAARLLVRL FPELFTQENL RLQYNHSGAC NKKQLDPVRL RLIRHYVEAV
     YPVDKMEEVW HYECVPSIDE RCRRPNRKKC DILKKAKRSS TVT
//