ID A0A3P8WHU7_CYNSE Unreviewed; 703 AA.
AC A0A3P8WHU7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein CASP {ECO:0000256|ARBA:ARBA00018691};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000027058.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000027058.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000027058.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the CASP family.
CC {ECO:0000256|ARBA:ARBA00006415}.
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DR RefSeq; XP_008307912.1; XM_008309690.2.
DR AlphaFoldDB; A0A3P8WHU7; -.
DR STRING; 244447.ENSCSEP00000027058; -.
DR Ensembl; ENSCSET00000027421.1; ENSCSEP00000027058.1; ENSCSEG00000017266.1.
DR GeneID; 103378465; -.
DR CTD; 445120; -.
DR GeneTree; ENSGT00940000163742; -.
DR InParanoid; A0A3P8WHU7; -.
DR OrthoDB; 74668at2759; -.
DR Proteomes; UP000265120; Chromosome 4.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR012955; CASP_C.
DR PANTHER; PTHR14043; CCAAT DISPLACEMENT PROTEIN-RELATED; 1.
DR PANTHER; PTHR14043:SF15; SIMILAR TO CCAAT DISPLACEMENT PROTEIN ISOFORM B; 1.
DR Pfam; PF08172; CASP_C; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 651..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 449..672
FT /note="CASP C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08172"
FT REGION 277..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 534..582
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 290..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 703 AA; 80479 MW; 4E3360F35C757E03 CRC64;
MTARSSPLNS NPRALYQHLI PVSICLKMAA NAGSMFQYWK RFDLQQLQKE LDTTATQLAN
RQDESEQSRK KLIDLSREFK KNTPEDFRKQ VAPLLKSFQG EIDALSKRSK EAEAAFLNVY
KKIIDVPDPV PVLELAQQLQ LKLQRMHDIE TENTKLRETL EDYNKEFAEV KNQEVTIKAL
KEKIREYEQS LKNQAENLAQ EKQLQLHNDY AEKERKLQES QDSMSSRLKE AEQKAQTLQT
ALETTQAELF DLKTKYDEES TAKADEIEMV MTDLERANQR AETAQREAES LREQLSLSNQ
SQQLGSPDKS DTITEQEAEV TSHSSLEAEL RAKERETAQL VEDVQRLQAS LTKLRETTSS
QISQLEQQLS SKTAVLKELE EKLKKQADYE EVKKELSILK SMEFGTSDSV QDSSKPLEVL
LLERNRSLQS ESAALRIANT ELSGRYADLQ VEFSSAVRTS AEQKELILKL EHDLSTIQAM
SSLSRPDADG SEVANMGRIP EPIKEATAMF TSTDLGSVLT PHAELPQGQM DSLLSIISSQ
RERFRSRNQE LEAENRSLQQ TMQALQNELD SLRADNIKLY EKIKFLQSYP SKAAGSDDTV
MRYSSQYEER LDPFASFSKK ERQRRYLSLS PWDKATLGLG RVILSNKTAR TIAFFYTLFL
HLLVFLVLYK TAWSESIGRD CTAFCAKQYA DHLHRFHEND QHL
//
