ID A0A3P8WLM3_CYNSE Unreviewed; 433 AA.
AC A0A3P8WLM3;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Arf-GAP domain and FG repeat-containing protein 1 {ECO:0000313|Ensembl:ENSCSEP00000027367.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000027367.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000027367.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000027367.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_008332298.1; XM_008334076.2.
DR AlphaFoldDB; A0A3P8WLM3; -.
DR Ensembl; ENSCSET00000027734.1; ENSCSEP00000027367.1; ENSCSEG00000017473.1.
DR GeneID; 103396112; -.
DR CTD; 393560; -.
DR GeneTree; ENSGT00940000155511; -.
DR OrthoDB; 2891604at2759; -.
DR Proteomes; UP000265120; Chromosome 20.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08857; ArfGap_AGFG1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46134:SF5; ARFGAP WITH FG REPEATS 1B; 1.
DR PANTHER; PTHR46134; DRONGO, ISOFORM F; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 11..135
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 137..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 45906 MW; 14F90D826B4FDB78 CRC64;
MTTSAKRKQE ETHLKMLREM TSLPANRKCF DCDQRGPTYV NMTVGSFVCT TCSGILRGLN
PPHRVKSISM TTFTQQEIEF LQKHSNEVCK HIWLGLYDDR TSVVPDFREP QKVKEFLQEK
YEKKRWYVPP DQARSVGSVQ ASVSGSSASS TGSTPEVQPL KSLQLNKTPL RQSPGLSRSQ
AQSASQEKKF DLLSDLGGDI FAAPPTQTAT SSNFANFAHF PNQTGGGVPI PSMSSAVPAQ
PLGGSCKEDR YAALAELDNE LSSSVSSGSN VQGNLFGPVL GSSPAQNQPV LPNMQPGFGA
VPSTNPFVAA AVAPDMATNP FQTNGRASAA APFGTGSMSM PAGFGSASSY CLPTSFSGTF
QQQFPGQAPI PYAQPGAYHP QSNGPAFPVY TQNKPSMPFG QHMAAPGMSN NPFMAGGPAG
AFPSGGSSTN PFL
//
