ID A0A3P8WXM4_CYNSE Unreviewed; 340 AA.
AC A0A3P8WXM4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=G1/S-specific cyclin-D1-like {ECO:0000313|Ensembl:ENSCSEP00000032163.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000032163.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000032163.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000032163.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with the CDK1 protein kinase to form a
CC serine/threonine kinase holoenzyme complex also known as maturation
CC promoting factor (MPF). The cyclin subunit imparts substrate
CC specificity to the complex. {ECO:0000256|ARBA:ARBA00025821}.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
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DR RefSeq; XP_008327395.1; XM_008329173.2.
DR AlphaFoldDB; A0A3P8WXM4; -.
DR STRING; 244447.ENSCSEP00000032163; -.
DR Ensembl; ENSCSET00000032583.1; ENSCSEP00000032163.1; ENSCSEG00000020651.1.
DR GeneID; 103392544; -.
DR KEGG; csem:103392544; -.
DR CTD; 567411; -.
DR GeneTree; ENSGT00940000167404; -.
DR InParanoid; A0A3P8WXM4; -.
DR OMA; YMPSMLY; -.
DR OrthoDB; 1077601at2759; -.
DR Proteomes; UP000265120; Chromosome 17.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10177:SF262; CYCLIN DX; 1.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00022618};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cyclin {ECO:0000256|ARBA:ARBA00023127, ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 102..186
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 195..313
FT /note="Cyclin C-terminal"
FT /evidence="ECO:0000259|SMART:SM01332"
FT REGION 310..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 340 AA; 37968 MW; 2F78E5D8B5F13B35 CRC64;
MEDLQGCQLK DTTSAGFCTH RVVQMDLSLW CEEVDDDLRQ EQVQNLEPVA RGSTPLRATW
DPTVSGNRVI QKLLHVEERY LPSALYIALI QRNPQQREEL TKWALDVCFE CGCDEAVFPL
SISLIDRFLS ASLSLPISPY CLAAGCILIA SKLIECDNVT ADALCAAVEN NFEASSLREM
ERVILATLRW DTAAVTPQDF LPHFLVSVAE GERARGNDTN EEDEEELLST LRRHSDTLAV
MCVCDSRFLG VPPSLVAAAS LVCALRGLGK KGVTQLERTS ETLAELCQSD LAVLQYYSEM
IEYGLHHRLR SSPQIGPSEK DEEVEDERAR TPTDMREINF
//
