ID A0A3P8WXQ2_CYNSE Unreviewed; 495 AA.
AC A0A3P8WXQ2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Si:ch1073-90m23.1 {ECO:0000313|Ensembl:ENSCSEP00000031539.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000031539.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000031539.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000031539.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8WXQ2; -.
DR Ensembl; ENSCSET00000031949.1; ENSCSEP00000031539.1; ENSCSEG00000020193.1.
DR GeneTree; ENSGT00940000166290; -.
DR InParanoid; A0A3P8WXQ2; -.
DR OMA; RCEFPPP; -.
DR Proteomes; UP000265120; Chromosome 13.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15711:SF1; RAP1 GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120}.
FT DOMAIN 160..378
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
SQ SEQUENCE 495 AA; 55617 MW; E3667047167D4B55 CRC64;
AALVHQGSRI NEQRCEFPLP LKVIRASSVL FLFQSQFLTA GGGWPLIVPS ETGGYWIQPP
LDGGLVSVSP TSPGQSPDLD NYDIMERDRE ATVYRQVFCT RVRRPGGQTL VPMTNQKKKD
VRSLDLSFSQ GRVLLTCLTR VNEKIRYIFS SLNFKAPELI TAFDEHRVSL NFKFGILYQR
EGQLSEEEIL SNNHESDDFK EFLSILGETV LLQGFTRFRG GLDVSHGQTG SEAVFTSFQG
REIMFHVATK LPFTEGDPQQ LQRKRHIGND IVALIYQEGQ TPFFSDIIKS QFLHCFLVVR
RIQSEEDAGG AAYQVSVTAR DDVPPFGPVI PDPPVFTDPS LLRQFLLTKL INAEISCYKA
ECFSRLELRT RSLLLETLQA ELSTRSQCMM GDSSLSALSC SDSVRAASEG SGGFIENFKR
AIRVRSHSLD MLGAPKKMSG GAPQKPKVRR KRLSLDKGGW TKPKPVIFIL LNFPHRHRKM
EKGKTSEQVK NYFSK
//
