ID A0A3P8WZM1_CYNSE Unreviewed; 527 AA.
AC A0A3P8WZM1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Selenoprotein O {ECO:0000256|ARBA:ARBA00031547};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000030140.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000030140.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000030140.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the SELO family.
CC {ECO:0000256|ARBA:ARBA00009747}.
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DR AlphaFoldDB; A0A3P8WZM1; -.
DR STRING; 244447.ENSCSEP00000030140; -.
DR Ensembl; ENSCSET00000030544.1; ENSCSEP00000030140.1; ENSCSEG00000019299.1.
DR GeneTree; ENSGT00390000005508; -.
DR InParanoid; A0A3P8WZM1; -.
DR OMA; YGPYGWL; -.
DR Proteomes; UP000265120; Chromosome 3.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR HAMAP; MF_00692; SelO; 1.
DR InterPro; IPR003846; SelO.
DR PANTHER; PTHR12153; SELENOPROTEIN O; 1.
DR PANTHER; PTHR12153:SF18; SELENOPROTEIN O; 1.
DR Pfam; PF02696; SelO; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 527 AA; 59699 MW; 4F989873646C988A CRC64;
SCLLWQQHRN INYEQTSIVS CFAEAFPVDD VDGNFVRTVK DCIFSKSIPT PLKGPLRLAA
VSKEVVEETL DLDVVLTQSE DFLQFASGGK LMSGSVPLTH RYGGHQFGYW AGQLGDGRAH
LLGQYLNRKG ETWELQLKGS GKTPYSRSGD GRAVIRSSVR EFLCSEAMHF LGVPTSRAAS
LIVSEEPVLR DQFYNGNVDT ERGAVVLRVA KSWFRFGSLE ILAKSGETDL LRKLLDFVIE
EHFPSIVSDD PDKYLVFYST VVNETAHLIG QWMSIGFAHG VCNTDNFSLL SITIDYGPFG
FMEAYDPNFV PNSSDDEGRY RIGAQADVGL FNLQKLQEAL NPVLTQKQQR AANMILKGFT
GIYQMRIQQL FRGKLGLRDE DEEDGLLIAL LLKMMEETKS DFTMTFRQLS EASQLQLHSR
NVSQMWALYD LSQHVHFSDW LRMYLLRISR LKKSRSFNKK CVNPRYVLRN WMAELAIRKA
EKNDFSQVAM LHRILASPFV TQTTAEDAGY ASRPPRWSQR LKVSCSS
//
