ID A0A3P8X2W4_CYNSE Unreviewed; 530 AA.
AC A0A3P8X2W4;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Adenylate kinase 5 {ECO:0000313|Ensembl:ENSCSEP00000033364.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000033364.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000033364.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000033364.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the adenylate kinase family.
CC {ECO:0000256|ARBA:ARBA00007220, ECO:0000256|RuleBase:RU003330}.
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DR AlphaFoldDB; A0A3P8X2W4; -.
DR Ensembl; ENSCSET00000033798.1; ENSCSEP00000033364.1; ENSCSEG00000021408.1.
DR GeneTree; ENSGT00940000155917; -.
DR OMA; NGLVHIC; -.
DR Proteomes; UP000265120; Chromosome 20.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01428; ADK; 2.
DR CDD; cd22978; DD_AK5; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_00235; Adenylate_kinase_Adk; 1.
DR InterPro; IPR000850; Adenylat/UMP-CMP_kin.
DR InterPro; IPR033690; Adenylat_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23359:SF79; ADENYLATE KINASE ISOENZYME 5; 1.
DR PANTHER; PTHR23359; NUCLEOTIDE KINASE; 1.
DR Pfam; PF00406; ADK; 2.
DR PRINTS; PR00094; ADENYLTKNASE.
DR SUPFAM; SSF47391; Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00113; ADENYLATE_KINASE; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU003330};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003330}.
SQ SEQUENCE 530 AA; 59865 MW; 5D98EBBE11791632 CRC64;
MNTNDAKEYL ARREIPQLFE SLLTGLMYHR PDDPIDYLES CLKKVRELGG TDKVRWDTFV
GQEKKSLPPL NGGQSRRSIF RNVLPDSPNF PYRRYDRLPP ISQFSIESDS DLSETAELIE
EYEVFDPSRP RPKVILVIGG PGSGKGTQSL KIAERYGFHY VSVGELLRKK MIHNATSNRK
WSLIAKIITN GELAPQETTI TEIKQRIMKI PDANGIVIDG FPRDVGQALS FEDQICTPDL
VMFLACTSHR LKERLQKRAE QQGRPDDNPK AIERRLTNFK QNTIPLVQYF QERGLIVTLD
ADRDEEEVFC DISMTLDNKL FSSKEPTAAS TRPRGVTVEM LCVCVFPGGP GSGKSLQCQR
MEERFGLRHM TLGDLLCNEL QSQSERGRHL REMLEGGEQL PRVSDTLLEL LGDAVAASVH
QRPGRGLVIS SFPRDLLQAE EYEAKVADPS AVLLLSCSPK TLSTRLQCRR RSSTDRDSAT
HRTLESFTDN SQEVAAYYQR KRLLHTIDAE GSPDEVFTQI LQALESSSIF
//
