ID A0A3P8X354_CYNSE Unreviewed; 328 AA.
AC A0A3P8X354;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Apolipoprotein L, 1 {ECO:0000313|Ensembl:ENSCSEP00000033257.1};
OS Cynoglossus semilaevis (Tongue sole).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae;
OC Cynoglossinae; Cynoglossus.
OX NCBI_TaxID=244447 {ECO:0000313|Ensembl:ENSCSEP00000033257.1, ECO:0000313|Proteomes:UP000265120};
RN [1] {ECO:0000313|Ensembl:ENSCSEP00000033257.1, ECO:0000313|Proteomes:UP000265120}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24487278;
RA Chen S., Zhang G., Shao C., Huang Q., Liu G., Zhang P., Song W., An N.,
RA Chalopin D., Volff J.N., Hong Y., Li Q., Sha Z., Zhou H., Xie M., Yu Q.,
RA Liu Y., Xiang H., Wang N., Wu K., Yang C., Zhou Q., Liao X., Yang L.,
RA Hu Q., Zhang J., Meng L., Jin L., Tian Y., Lian J., Yang J., Miao G.,
RA Liu S., Liang Z., Yan F., Li Y., Sun B., Zhang H., Zhang J., Zhu Y., Du M.,
RA Zhao Y., Schartl M., Tang Q., Wang J.;
RT "Whole-genome sequence of a flatfish provides insights into ZW sex
RT chromosome evolution and adaptation to a benthic lifestyle.";
RL Nat. Genet. 46:253-260(2014).
RN [2] {ECO:0000313|Ensembl:ENSCSEP00000033257.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the apolipoprotein L family.
CC {ECO:0000256|ARBA:ARBA00010090}.
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DR AlphaFoldDB; A0A3P8X354; -.
DR STRING; 244447.ENSCSEP00000033257; -.
DR Ensembl; ENSCSET00000033686.1; ENSCSEP00000033257.1; ENSCSEG00000021347.1.
DR GeneTree; ENSGT01030000234599; -.
DR InParanoid; A0A3P8X354; -.
DR OMA; WRTKVAQ; -.
DR Proteomes; UP000265120; Chromosome 20.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR InterPro; IPR008405; ApoL.
DR PANTHER; PTHR14096; APOLIPOPROTEIN L; 1.
DR PANTHER; PTHR14096:SF59; APOLIPOPROTEIN L, 1 ISOFORM X1; 1.
DR Pfam; PF05461; ApoL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265120};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 219..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 278..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 35816 MW; FC5C2C9974BA16F5 CRC64;
PQEDDMTEKE EAKAFAVTAD KVQKGIRVFN KLFSERAESL WQHVIDLNAI ADGLDKFNKK
TKIAQITGGS TSAIGGVATI AGLALAPITM GTSLIVTAVG LGVATAGGLT SAGAGISNQV
NNSLDRKKVE KIVQDYQKQM VDLNKCLKFI KQGIENLRRF DLIKMKNHAY NNDFPVLSSR
FYEDGAMAGK AILINANEIM RVVQIANVAG STAARAVQIA SMATGVLTGL FVGMDIYFVA
KDSKELKKGA KSEFAAKIRE VSMQLHDGLV ELNSLREELQ STSSEDKDTA DVDSEKKEKD
NKYDSSEEDE IDRIKKAIKK DIENREYV
//
