ID A0A3P8XDT5_ESOLU Unreviewed; 291 AA.
AC A0A3P8XDT5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Leucine-rich repeat-containing protein 38 {ECO:0000313|Ensembl:ENSELUP00000001758.1};
GN Name=LRRC38 {ECO:0000313|Ensembl:ENSELUP00000001758.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000001758.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000001758.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000001758.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010874053.1; XM_010875751.2.
DR AlphaFoldDB; A0A3P8XDT5; -.
DR STRING; 8010.ENSELUP00000001758; -.
DR Ensembl; ENSELUT00000016854.2; ENSELUP00000001758.1; ENSELUG00000003189.2.
DR GeneID; 105013899; -.
DR KEGG; els:105013899; -.
DR GeneTree; ENSGT00940000162571; -.
DR InParanoid; A0A3P8XDT5; -.
DR OMA; RCLCPDH; -.
DR OrthoDB; 3325405at2759; -.
DR Proteomes; UP000265140; LG12.
DR Bgee; ENSELUG00000003189; Expressed in camera-type eye and 3 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR46473; GH08155P; 1.
DR PANTHER; PTHR46473:SF4; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 38; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 3.
DR SMART; SM00082; LRRCT; 1.
DR SMART; SM00013; LRRNT; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..291
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018278649"
FT TRANSMEM 247..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..58
FT /note="LRRNT"
FT /evidence="ECO:0000259|SMART:SM00013"
FT DOMAIN 185..239
FT /note="LRRCT"
FT /evidence="ECO:0000259|SMART:SM00082"
SQ SEQUENCE 291 AA; 32111 MW; F0C0D9BBE8250149 CRC64;
MLPCINWLQP FLALLSSTLL TRGHNCPSSC LCPDHHTVDC QGQGLTRLPS PIPLDVRRLL
LSDNWIPLIP SDFLVLYSDL VYLDLRNNSL SALEPGTLST SSRLVYLDLG SNNLTEIQSG
TFGETQSLIK LRLGNNPYLS LVEEDAFVGL TSLRELELER NGLQGLDVGA LEPLTSLRVL
RLEGNPWVCN CHFAKLFVWL TENRHKLPTG MEGLECSLPM DGSLMSLSLL TEASFRECRG
YLSLTDILIV IFSGISVSVV AIIASFFLAS MVHCFQRLGK AGQTDEEEGN D
//
