ID A0A3P8XIB5_ESOLU Unreviewed; 526 AA.
AC A0A3P8XIB5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Notochord granular surface {ECO:0000313|Ensembl:ENSELUP00000004305.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000004305.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000004305.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000004305.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8XIB5; -.
DR STRING; 8010.ENSELUP00000004305; -.
DR Ensembl; ENSELUT00000012576.2; ENSELUP00000004305.2; ENSELUG00000005514.2.
DR GeneTree; ENSGT00940000164536; -.
DR InParanoid; A0A3P8XIB5; -.
DR OMA; NREAEQM; -.
DR Proteomes; UP000265140; LG18.
DR Bgee; ENSELUG00000005514; Expressed in bone element and 11 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:Ensembl.
DR GO; GO:0060035; P:notochord cell development; IEA:Ensembl.
DR GO; GO:0048570; P:notochord morphogenesis; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR006821; Intermed_filament_DNA-bd.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF11; NOTOCHORD GRANULAR SURFACE-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF04732; Filament_head; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 117..427
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 37..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 121..155
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 198..260
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 325..412
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 56..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 452..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 526 AA; 60134 MW; A8ED5D4429053739 CRC64;
PTNYHRFQVV IMSRSPERMS SYRRHFEAAF APSSCYQVRV SSPSPTRKDS RHRSASYSRS
GGTMGRRNLS SGRKSRMTSS VSMGALCFGM NMGLGPKLDL DAATAKNQEF MNTRSGERQE
MVDLNDRLAL YIEKVRTLEG QNMLLEAEID ALQNRYVKPS GLRLLYEGQL RELHRLAEQT
REQRDLSVAA KGAMAGQLEV LKVKYEEALE ARKKAEMEID AFRPDVDKAT SARITLEKHL
ENLEVELAFL TRVHKEEIDE LMQKIYVAVA KVDMNFALPD LSSALKQIQS QYDSIAARNL
QEMDAWYKSK FQDLNNVTSK HVKSVRSVRE EIARYKKDLL NLERELESLK TRNESLENQI
RDAVERQKKE EEALLERIEE LKLELKMMKE KIALLLREYQ ELLNVKMALE MEITTYRALI
EGEDIRLSTL VQTMSLGRGG MVISARMGAS STSDDDSRKT KEAPDRGAEA ILSGSKTESY
DEQSVEMTER KTVLMRTVKT DADTYERDTQ ERTIIISGAA DYIDEE
//
