ID A0A3P8XLP5_ESOLU Unreviewed; 630 AA.
AC A0A3P8XLP5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=MYB proto-oncogene, transcription factor {ECO:0000313|Ensembl:ENSELUP00000005476.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000005476.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000005476.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000005476.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_010881375.2; XM_010883073.3.
DR AlphaFoldDB; A0A3P8XLP5; -.
DR STRING; 8010.ENSELUP00000005476; -.
DR Ensembl; ENSELUT00000010603.2; ENSELUP00000005476.1; ENSELUG00000006491.2.
DR KEGG; els:105018000; -.
DR GeneTree; ENSGT00940000156248; -.
DR InParanoid; A0A3P8XLP5; -.
DR OMA; WEPATCG; -.
DR OrthoDB; 20023at2759; -.
DR Proteomes; UP000265140; LG18.
DR Bgee; ENSELUG00000006491; Expressed in nose and 13 other cell types or tissues.
DR GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0043009; P:chordate embryonic development; IEA:Ensembl.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR GO; GO:0001654; P:eye development; IEA:Ensembl.
DR GO; GO:0035701; P:hematopoietic stem cell migration; IEA:Ensembl.
DR GO; GO:0045658; P:regulation of neutrophil differentiation; IEA:Ensembl.
DR CDD; cd00167; SANT; 3.
DR Gene3D; 1.10.10.60; Homeodomain-like; 3.
DR InterPro; IPR015395; C-myb_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR012642; Tscrpt_reg_Wos2-domain.
DR PANTHER; PTHR45614; MYB PROTEIN-RELATED; 1.
DR PANTHER; PTHR45614:SF5; TRANSCRIPTIONAL ACTIVATOR MYB; 1.
DR Pfam; PF09316; Cmyb_C; 1.
DR Pfam; PF07988; LMSTEN; 1.
DR Pfam; PF00249; Myb_DNA-binding; 3.
DR SMART; SM00717; SANT; 3.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51294; HTH_MYB; 3.
DR PROSITE; PS50090; MYB_LIKE; 3.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 35..86
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 35..86
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 87..142
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 87..138
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 139..189
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 143..193
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT REGION 338..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 386..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..485
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 630 AA; 71073 MW; 72DF454E9400D6E6 CRC64;
MARRPRHSVY SSDEDEDDME LYEHDYDGPL AKAGKRNLGK TRWTREEDEK LKKLVEHHGS
EDWKRIASFL PNRTDVQCQH RWQKVLNPEL IKGPWTKEED QRVIELVQKY GAKRWSVIAK
HLKGRIGKQC RERWHNHLNP EVKKTSWTEE EDRIIYQAHE KLGNRWAEIA KLLPGRTDNA
IKNHWNSTMR RKVEQEGYLQ HAAKSGSTSH SVAPGYGKSN HHIMSYSPLP AHSPLSAHSP
LPGNYSFISD HRLPFPLGLH VNIRNIPQHG TAAIQRHYQE EDPEKEKRVK EIELLLMSTE
NELKGQPALP LIPYNGWAGS DSSEGVATSC HHHQAAAPCL PEESASSSRN NNNNNNNSNH
GSHGLSNLPE FMDSVIDSTC SSLSELTTSQ LSDRSSSRTD RGSPNQGSGT DNAGFSFASF
ICSTPKRSPV RNLHFSPSQF LNQSTTLEHP DPDGLPISSQ KPLVTSPNHR DHTPRPQKEN
DLFRTPSIRR SLLELSPRTP TPFRSTVVEC IKQEPMECLV SRSSSPEPPL KKIKQEVESP
CERSPCLQWE GSDLHTQLFS PSGPAQEVPD LLTSSGLSED GHKAHHAPLR PLGSPLQGLN
IWDQVTCGKV EDQEQNHKYI NTYSARTLVM
//
