ID A0A3P8XM74_ESOLU Unreviewed; 693 AA.
AC A0A3P8XM74;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Erythrocyte membrane protein band 4.1-like 3b {ECO:0000313|Ensembl:ENSELUP00000005646.2};
GN Name=EPB41L3 {ECO:0000313|Ensembl:ENSELUP00000005646.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000005646.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000005646.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000005646.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8XM74; -.
DR Ensembl; ENSELUT00000010313.2; ENSELUP00000005646.2; ENSELUG00000006710.2.
DR GeneTree; ENSGT00940000157047; -.
DR Proteomes; UP000265140; LG03.
DR Bgee; ENSELUG00000006710; Expressed in heart and 15 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF20; BAND 4.1-LIKE PROTEIN 3; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 2.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT DOMAIN 74..349
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 77406 MW; 81AFAE6AFF6DB154 CRC64;
MTTESGADSE PKQQQDKDWT EKKEKTSEHF PTVVGYSTPA KKNQLEEDLS STRSSTSRLS
IKSPLRGVKK LKNMQCKVTL LDGSDYTLTV DKRARGQLLF AKVCDHLNLL ETDYFGITYR
DVENQKVQRD SSQVSVCGPW NFAFNVKFYP PDPAQLSEDI TRYYLCLQLR DDVVSGRLPC
SFATHTVLGS YTVQSELGDY DPEETTYSSE LRFAPNHTKE LEDKVMELHK THKGMTPAQA
EMHFLENAKK LSMYGVDLHH AKDSEGVEIM LGVCSSGLLI YRDRLRINRF AWPKVLKISY
KRNNFYIKIR PGEFEQFEST IGFKLPNHRA AKRLWKTCVE HHTFFRLVSP EAPPKNFLGL
GSKFRYSGRT QAQTRRVSSQ IIRAAPIFER SSSKRYTMSR SLDGAPGTEN HDALMRDATP
AKAINAGDLI TTVTPEKKAE EEKAEEEEGQ ANAAETTEPN VPSTPLRQEN KTDSEQTDFA
FDGETTVTEV GRARLCMPHC VLSGSLPQGT RVIDLRSGFV RLTSNTSKYL SCDETVTYLA
GPFPWAFCHP DSLINPGFCV LCAPFSLQKS PAVPQVELST KEVPVVHTET KTITYESGNA
NGDSDPGVLM SAQTITSETT STTTTTHITK TVKGGISETR IEKRIVITGD AGDIDHDQAL
AQAIKEAKEQ HPDMSVTKVV VHKETEITPE GED
//
