ID A0A3P8XUX0_ESOLU Unreviewed; 534 AA.
AC A0A3P8XUX0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM39 {ECO:0000313|Ensembl:ENSELUP00000007539.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000007539.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000007539.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000007539.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3P8XUX0; -.
DR Ensembl; ENSELUT00000007083.2; ENSELUP00000007539.1; ENSELUG00000008340.2.
DR GeneTree; ENSGT01040000240400; -.
DR Proteomes; UP000265140; LG24.
DR Bgee; ENSELUG00000008340; Expressed in ovary and 3 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19802; Bbox1_TRIM8-like; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF34; TRIPARTITE MOTIF-CONTAINING 80; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 14..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 144..184
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 315..525
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 534 AA; 60006 MW; 031EF858137894A7 CRC64;
MASCSVLTED QFSCAICFGV LTDPATIPCG HTFCMACLQG YWASIERPPV CALCKRGFTS
GLDIQVNITL RDLVETFKGM NGGVAAHRLP AAPGEVSCDV CLGERQDKAV KTCLVCLSSY
CQNHIRAHNA RFSRHQLVSP LANLGERICP THERLLERYC RTDRTMLCVA CDAHQEPGHE
VVTMQREFLS QKDEAERQIQ SWTMFCKDRF YHERQIWEHY NAEARKTLSE MESTASRESR
ALAEGIATLK GRAAELERVI DSSDSFELLK SLPSLPPGPP SGDRVPCTVF TTNLLADVWM
ASLEEMAILP KMHTFWLTNS GFSELAAVKE FTVEVTPDPS TAHPSLLFRR GCREIRVDRT
KMDYTYPKSA QRFTQVPCVL STKGFTSQNA YWEVELSDRA RNGSSVWCVG LAVQSSMITI
SRWHSLTPDK GFWVLEHRDG KLWPVTTPPT TTALSIKSST CKVHLGVFFD GRQRRLSFYD
VPLGRHLYTY DISAPMLINQ VVYPVFSPDL FSPGLNQINI MNVTALTAKK HRCH
//
