ID A0A3P8XWV7_ESOLU Unreviewed; 167 AA.
AC A0A3P8XWV7;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=C-type natriuretic peptide 3-like {ECO:0000313|Ensembl:ENSELUP00000008270.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000008270.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000008270.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000008270.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU003686}.
CC -!- SIMILARITY: Belongs to the natriuretic peptide family.
CC {ECO:0000256|ARBA:ARBA00009041, ECO:0000256|RuleBase:RU003686}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_010873852.2; XM_010875550.2.
DR AlphaFoldDB; A0A3P8XWV7; -.
DR STRING; 8010.ENSELUP00000031438; -.
DR Ensembl; ENSELUT00000005839.2; ENSELUP00000008270.1; ENSELUG00000008985.2.
DR GeneTree; ENSGT00530000065390; -.
DR InParanoid; A0A3P8XWV7; -.
DR OMA; RNVPYYV; -.
DR OrthoDB; 4257928at2759; -.
DR Proteomes; UP000265140; LG12.
DR Bgee; ENSELUG00000008985; Expressed in heart and 2 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR GO; GO:0097746; P:blood vessel diameter maintenance; IEA:UniProtKB-KW.
DR InterPro; IPR002406; C_natriurtcpep.
DR InterPro; IPR000663; Natr_peptide.
DR InterPro; IPR030480; Natr_peptide_CS.
DR PANTHER; PTHR12167; C-TYPE NATRIURETIC PEPTIDE; 1.
DR PANTHER; PTHR12167:SF5; C-TYPE NATRIURETIC PEPTIDE 3-LIKE PRECURSOR; 1.
DR Pfam; PF00212; ANP; 1.
DR PRINTS; PR00713; CNATPEPTIDE.
DR SMART; SM00183; NAT_PEP; 1.
DR PROSITE; PS00263; NATRIURETIC_PEPTIDE; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Vasoactive {ECO:0000256|ARBA:ARBA00022858, ECO:0000256|RuleBase:RU003686}.
SQ SEQUENCE 167 AA; 18565 MW; E5DDE088782163DC CRC64;
MSRLDETHRY KSAPGDVAIR IGEGNGLDNL KRQVETTNYI KMISNIQFCC LSVLVLLNLV
GAKPVSNLQS LKELLEESNV PYYGSEESEV DDKDLNTEKE AFTGEVVQPW LTEDRSALTG
KENAVARLLS DIMTTPKRSW GRFKKGGMRS CFGVRLERIG SFSGLGC
//
