ID A0A3P8Y0V8_ESOLU Unreviewed; 687 AA.
AC A0A3P8Y0V8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Interleukin enhancer binding factor 3 {ECO:0000313|Ensembl:ENSELUP00000009730.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000009730.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000009730.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000009730.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_010873294.1; XM_010874992.3.
DR AlphaFoldDB; A0A3P8Y0V8; -.
DR Ensembl; ENSELUT00000003343.2; ENSELUP00000009730.1; ENSELUG00000000372.2.
DR GeneID; 105013448; -.
DR GeneTree; ENSGT00940000156719; -.
DR OrthoDB; 4565640at2759; -.
DR Proteomes; UP000265140; LG11.
DR Bgee; ENSELUG00000000372; Expressed in embryo and 14 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd19910; DSRM_ILF3_rpt1; 1.
DR CDD; cd19912; DSRM_ILF3_rpt2; 1.
DR Gene3D; 1.10.1410.40; -; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR033099; DSRM1_ILF3.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR InterPro; IPR043519; NT_sf.
DR PANTHER; PTHR45762:SF4; INTERLEUKIN ENHANCER-BINDING FACTOR 3; 1.
DR PANTHER; PTHR45762; ZINC FINGER RNA-BINDING PROTEIN; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..376
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT DOMAIN 400..469
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 533..599
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 336..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..654
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 74986 MW; A427EB25637C308E CRC64;
MPPPLRHRSM RIFMNDDRHV MAKHSAVYPT QEELEGVQNM VSHTERALKA VSDWLDEQEK
VVVKTESDVA EPDKEGEPRV SEQATRSLRG VMRVGLVAKG LLLKGDLDLE LVLLCKDKPT
VTLLKKVSDN LDVQLKSITE DKYEVTQVIR DATIVIKSTK DPPLTLTINM TSPLVREEVE
KQAAGETLSV NDPPDVLDRQ KCLTALASLR HAKWFQARAN GLRSCVIVIR ILRDLCSRVP
TWAPLRGWPL ELLCEKAIGT GNRPMGAGEA LRRVLECLAS GILMADGAGI CDPCEKELTD
AIGHLDLQQR EDITQSAQHA LRLSAFGQLH KVLGMDPLPS KMPRKPRSET PIDYTVQIPP
STTYAPPMKR PIEEEEGGDD KSPNKKKKKL QKKSPDEKSE PPQAMNALMR LNQLKPGLQY
KLLSQTGPVH VPVFTMAVEV DGKSFEASGP SKRTAKLHVA VKVLQDMGLP TGVELKTTEP
VKTEEATAAA VVEEVKPCVT PVEMDTAATG AASAEATDSA ESARQQGPIL TKHGKNPVME
LNEKRRGLKY ELISETGGSH DKRFVMEVEI DGQKFQGTGS NKKVAKAYAA LAALDKLFPE
GSLTEAAKKK KLPPMHNPGF GMMGGPTGDP AATHRGRGRG GRGRGRGRGF NNGGGYSQGG
YGSYGYGNNG NYSDFVSDCY GYHEFAT
//
