ID A0A3P8Y2Z9_ESOLU Unreviewed; 293 AA.
AC A0A3P8Y2Z9;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transmembrane protein 178B {ECO:0000313|Ensembl:ENSELUP00000011032.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000011032.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000011032.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000011032.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TMEM178 family.
CC {ECO:0000256|ARBA:ARBA00008199}.
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DR RefSeq; XP_010861974.1; XM_010863672.2.
DR AlphaFoldDB; A0A3P8Y2Z9; -.
DR Ensembl; ENSELUT00000001152.2; ENSELUP00000011032.1; ENSELUG00000011462.2.
DR GeneID; 105005613; -.
DR KEGG; els:105005613; -.
DR GeneTree; ENSGT00390000015299; -.
DR InParanoid; A0A3P8Y2Z9; -.
DR OMA; RQHNSTN; -.
DR OrthoDB; 5296365at2759; -.
DR Proteomes; UP000265140; LG14.
DR Bgee; ENSELUG00000011462; Expressed in brain and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR039625; T178A/B.
DR PANTHER; PTHR32005:SF1; TRANSMEMBRANE PROTEIN 178B; 1.
DR PANTHER; PTHR32005; TRANSMEMBRANE PROTEIN 178B-RELATED; 1.
DR Pfam; PF13903; Claudin_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..293
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017950345"
FT TRANSMEM 173..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 293 AA; 33097 MW; E6D576D752D6832B CRC64;
MAAGKLLLYA GLSLSLCALG MLAVAICSDH WYETDARRYR ERCRSFSSRK NPGFIYIPNN
SLPLRASRSK LDRWEDKLLL ARNRRQLFAM SAADECSRQY NSTNMGLWSK CHRLGFDQDI
EDLIRKGMMA RCSYIKYHYS SATIPKNLSY NITKTIRQDE WHSLHLRRMT AGFMGMAVAI
ILFGWVIGVL GCCWDRGLMQ YVAGLLFLMG GTFCIISLCT CVAGINFELS RYPRYLYGLP
DDIGHGYGWS MFCAWGGLGL TLIAGFFCTL APSVQPLPRS TCPKSRQENG TVC
//
