ID A0A3P8YE78_ESOLU Unreviewed; 175 AA.
AC A0A3P8YE78;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Interleukin 17C {ECO:0000313|Ensembl:ENSELUP00000014416.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000014416.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000014416.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000014416.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-17 family.
CC {ECO:0000256|ARBA:ARBA00007236}.
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DR RefSeq; XP_010882467.1; XM_010884165.2.
DR AlphaFoldDB; A0A3P8YE78; -.
DR STRING; 8010.ENSELUP00000014416; -.
DR Ensembl; ENSELUT00000023208.2; ENSELUP00000014416.1; ENSELUG00000014447.2.
DR GeneID; 105018603; -.
DR KEGG; els:105018603; -.
DR GeneTree; ENSGT00940000166375; -.
DR InParanoid; A0A3P8YE78; -.
DR OMA; TYTQAVC; -.
DR OrthoDB; 2959916at2759; -.
DR Proteomes; UP000265140; LG19.
DR Bgee; ENSELUG00000014447; Expressed in stomach.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020440; IL-17_chr.
DR InterPro; IPR010345; IL-17_fam.
DR Pfam; PF06083; IL17; 1.
DR PRINTS; PR01932; INTRLEUKIN17.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..175
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018323436"
SQ SEQUENCE 175 AA; 20001 MW; 9951A4DA2B20D5D0 CRC64;
MPGLFKIMQT LLLLCIFIGG LSWASEARKL KGCFTAEELE SGALKIIRRH RYPTEDELKR
LHPNHSEKNC PTSLNARSLD YSHRSVSPWR YRIDSKEGRF PEKIAFAECL CKGCIIINGS
GHQAEDHNYN SVPIKQTQMV LEKTKCRNDP SKYSFISLYI EVPIACTCVK YRSST
//
