ID A0A3P8YFL5_ESOLU Unreviewed; 711 AA.
AC A0A3P8YFL5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Nucleolar protein 10 {ECO:0000256|ARBA:ARBA00015517};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000014685.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000014685.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000014685.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.
CC {ECO:0000256|ARBA:ARBA00005264}.
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DR AlphaFoldDB; A0A3P8YFL5; -.
DR Ensembl; ENSELUT00000039023.2; ENSELUP00000014685.2; ENSELUG00000014763.2.
DR GeneTree; ENSGT00390000007900; -.
DR Proteomes; UP000265140; LG15.
DR Bgee; ENSELUG00000014763; Expressed in embryo and 15 other cell types or tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14927:SF0; NUCLEOLAR PROTEIN 10; 1.
DR PANTHER; PTHR14927; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 483..509
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 525..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 711 AA; 81246 MW; 7AD245C96906A28B CRC64;
MQTSSVNDVK IYNLSHGKSL PEWLSDRKKR ALQKNDLDIQ RRIELIQDFE MPTVCTSIKV
SRDGQFILAA GTYKPRIRCY DTYQLSLKFE RCLDSDVVAF DILSDDYSKL VFLHCNRYVE
FHSQHGHYYK TRIPKFGRDF AYHYPSCDLY FVGASSEIFR LNLEQGRFLN SLQTDAVEHN
VCDINPVHHL LASGTAEGKV ECWDPRVRSR VGMLDCALSS VTEGTEVEGL PSVSALKFNG
SLTMAVGTST GQTLLYDLRS SRPLLVKDHF YGLPIKSVNF QDSLDLVLTA DSKIIKIWNK
DSGKVFSSIE PEANINDMCI YPGSGMLFTA NEAPKMNTFY IPSLGPAPRW CSFLDNLTEE
LEESPENTIY DDYKFVTRKD LENLGLSHLV GSALLRAYMH GFFMDIRLYH KVKTMANPFA
YEDYRKDKIR QKIEDSRAQR VQIKKLPKVN KELALKLMVE GDDEAELCTR KKKGKVGETH
TDDERFQVMF ENPDYQVEEQ SEEFRLLNPI VSKVGQKRRK KLQLLAKQAT DEDETEGRGS
SDESSDDDKS WVDEVREQRR LIYEEGRDRR RQERKQQDRN TTLLDEDSAQ NQTQGRKPGQ
QPRFFQIKAG EEFRSFGDVA HKQKLQKASL EERLKLEERS GTVNVADTAV GSKQFTFTLK
KVIKHCSVSL TFSPNSGGGC GPTCSDTKVL IHPPCKPVSL ACQLYFLNVI L
//
