ID A0A3P8YIH2_ESOLU Unreviewed; 322 AA.
AC A0A3P8YIH2;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Fibronectin type-III domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000015921.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000015921.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000015921.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010904270.1; XM_010905968.2.
DR AlphaFoldDB; A0A3P8YIH2; -.
DR STRING; 8010.ENSELUP00000015921; -.
DR Ensembl; ENSELUT00000025133.2; ENSELUP00000015921.1; ENSELUG00000001223.2.
DR GeneTree; ENSGT00510000051617; -.
DR InParanoid; A0A3P8YIH2; -.
DR OMA; EHANNAK; -.
DR OrthoDB; 4175169at2759; -.
DR Proteomes; UP000265140; LG20.
DR Bgee; ENSELUG00000001223; Expressed in pharyngeal gill and 15 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF50; INTERLEUKIN-10 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..322
FT /note="Fibronectin type-III domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018270966"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..97
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 110..195
FT /note="Interferon/interleukin receptor"
FT /evidence="ECO:0000259|Pfam:PF09294"
FT REGION 284..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 36387 MW; D55EB2956E9300BF CRC64;
MFCLKCVLSS WIVFQVITQA WSQEVPPPRD VRVDTSGVRW SPYTDRPGVK YTVQSQTDRG
EWRDIKGCVK TERTTCDNVS ACLMVRVWAQ QGNHRSESVQ ACTHAMSCSP EVQLTAQAGL
LLVTWRKNNN LSEEYADHFQ YQVEYGREGE ELKGSKRSRS SVMLQNLDVG GKYCVQARYT
CYQKAFGIPS PSQCAIIPES ESTKRIRISL ICVFISVLLG TVAVGLIFLF HKHYEKIKQL
HPRPLRLPDH YREFFNGDFN QQLMFPTSTS SPTEEHHDTI SIVVSEDDQI DSSPNSSASD
GEQGYNTPNE VESSAASLGH YE
//
