ID   A0A3P8YK78_ESOLU        Unreviewed;      1135 AA.
AC   A0A3P8YK78;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   02-DEC-2020, sequence version 2.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Nuclear GTPase SLIP-GC-like {ECO:0000313|Ensembl:ENSELUP00000016521.2};
OS   Esox lucius (Northern pike).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC   Esocidae; Esox.
OX   NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000016521.2, ECO:0000313|Proteomes:UP000265140};
RN   [1] {ECO:0000313|Ensembl:ENSELUP00000016521.2, ECO:0000313|Proteomes:UP000265140}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25069045;
RA   Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA   von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT   "The genome and linkage map of the northern pike (Esox lucius): conserved
RT   synteny revealed between the salmonid sister group and the Neoteleostei.";
RL   PLoS ONE 9:e102089-e102089(2014).
RN   [2] {ECO:0000313|Ensembl:ENSELUP00000016521.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_012991245.1; XM_013135791.2.
DR   RefSeq; XP_019906184.1; XM_020050625.1.
DR   AlphaFoldDB; A0A3P8YK78; -.
DR   STRING; 8010.ENSELUP00000016521; -.
DR   Ensembl; ENSELUT00000039803.2; ENSELUP00000016521.2; ENSELUG00000016356.2.
DR   GeneTree; ENSGT00390000007091; -.
DR   InParanoid; A0A3P8YK78; -.
DR   OMA; VWIVSEM; -.
DR   Proteomes; UP000265140; LG11.
DR   Bgee; ENSELUG00000016356; Expressed in nose and 6 other cell types or tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR025307; FIIND_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR47308; NUCLEAR GTPASE SLIP-GC; 1.
DR   PANTHER; PTHR47308:SF1; NUCLEAR GTPASE SLIP-GC; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   Pfam; PF13553; FIIND; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51830; FIIND; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT   DOMAIN          849..1121
FT                   /note="FIIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51830"
FT   REGION          60..137
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1112..1135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..99
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        100..119
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1135 AA;  128741 MW;  79384EFE59F795D1 CRC64;
     MASSFFVRDI LNKWNLSQWI KNFEEEEIDE EGFLLLEERE FIHLIPKVGP RTKFAHKHKE
     LVKKRKTHSN DDEVATSSTA SINATKSSST NSMPSTSVEK PLSEKRKHNV ADANKPKKKQ
     KSSAISRTTA MLDSEEKAEA KKIMQRVRSK LDEMPSTKLT DFLRSKIDML DKDRKEMVGV
     FGKTGAGKSS LINAILGETK LLPSGNQGAC TSVMIQVEAN MTNDKYIAEI EFITVQDWCD
     ELWSLQGKSC EKEDDDDKKM NFKHGDKDDD GKINALYGKE GLGKNVEELM DKKLFSKIPE
     FFSSHKKIVI CDTGEELSRK IACFTVSDSN SDTFEQLYWP LVKCLTIKVP NSKDLLEHVV
     LVDLPGNGDC NKSRDEMWKS FVGNCSAVWI VSDISRAISE KESWEILDST VTFFGPGGEC
     RSISFICTKT DDIEESQKDN AHSNILTRNE RTKKKVREKF NKQKDVKKHF SDADGLFKVF
     TVSSKKYNME KQNEPDEKEM TEEWMNALND TEIPHLQTFL RNLNDHRTRT SNYISGADWI
     LSLIQAVRNS DMKYSKEEVR QDLEQRLKDN LKSIGQYMEK PHKVFDQCLS KGVKQSEDSC
     KKLMNEVIAP EGISGSGYHR VVKCLCQNYG IYKPKRKSYT ENKNLNEHLA SYMRNCIADK
     FTYYFPNDKC GPIKEKIENF TLDTNSLVKK HKSLSLQLTF LKTEKELKTQ LICDILKKKK
     QIYLTLSESI KDSMHVSYEN ASMHTGKGSL QRMKDELHQH MKKANIFQKA KKDMLDGLTE
     LKDHILKQMK CKLQESIEIS LQTPNSSFLP DVTEDYNKIK ELMAHFCAIP VTTILDPHAK
     STGFQSQSLA GQKDVEEPRI INSQHIRRLT YRLQCPEAGL FQCGLTGLVF EMAGKGDVRV
     KISKWDTSVL GSMTPAGPLF SISCPAVLQL HLPHCMCDDE EILSVANFTG GKMEIVKPLK
     TTASHVVVNI PNPSLVGLIR CGLSTLPVQS QVLLFLCPQG NTNQKGMLNV FLLPKNVPIC
     KVKHQQKVSD FIQTSSECTL SPGRRYSLCC QLACWNVLMN VQFDSDYTRK LLPTFQVPLE
     CISDAKNMNL TLLDRETNDQ KVWEFVVQTS SITSPSVPAP SSGPSRLQRS TSPVY
//