ID A0A3P8YKS5_ESOLU Unreviewed; 177 AA.
AC A0A3P8YKS5;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Si:dkeyp-75b4.8 {ECO:0000313|Ensembl:ENSELUP00000017208.2};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000017208.2, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000017208.2, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000017208.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004125}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004125}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004125}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004630}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004630}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004630}.
CC -!- SIMILARITY: Belongs to the CDIP1/LITAF family.
CC {ECO:0000256|ARBA:ARBA00005975}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3P8YKS5; -.
DR STRING; 8010.ENSELUP00000017208; -.
DR Ensembl; ENSELUT00000026745.2; ENSELUP00000017208.2; ENSELUG00000016955.2.
DR GeneTree; ENSGT00940000155366; -.
DR InParanoid; A0A3P8YKS5; -.
DR OMA; THVEYKP; -.
DR Proteomes; UP000265140; LG09.
DR Bgee; ENSELUG00000016955; Expressed in pharyngeal gill and 2 other cell types or tissues.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR006629; LITAF.
DR InterPro; IPR037519; LITAF_fam.
DR PANTHER; PTHR23292; LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR; 1.
DR PANTHER; PTHR23292:SF45; LITAF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF10601; zf-LITAF-like; 1.
DR SMART; SM00714; LITAF; 1.
DR PROSITE; PS51837; LITAF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 130..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 91..177
FT /note="LITAF"
FT /evidence="ECO:0000259|PROSITE:PS51837"
SQ SEQUENCE 177 AA; 19449 MW; 5E9764F6019A3C5F CRC64;
MDNPSYADQP PPYTEATFYP PIPVTASPAN CSLHPNYSTP PPTYREAVTS QPDPFPVLTP
PTQQLTGIHL HQSTQIVNGA SFQQTNQRIP STVVYIDPVS VGPLGDAPCM TRCSNCRQNI
TTIVTYKPGM AAWSMCLLFT LLGLICGCCL IPFLLRGFQD AHHTCPLCHA HLYIHIR
//
