ID A0A3P8YNC8_ESOLU Unreviewed; 261 AA.
AC A0A3P8YNC8;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ER membrane protein complex subunit 3 {ECO:0000256|ARBA:ARBA00020822, ECO:0000256|PIRNR:PIRNR010045};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000018113.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000018113.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000018113.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276, ECO:0000256|PIRNR:PIRNR010045}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EMC3 family. {ECO:0000256|ARBA:ARBA00005376,
CC ECO:0000256|PIRNR:PIRNR010045}.
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DR RefSeq; XP_010879865.1; XM_010881563.2.
DR AlphaFoldDB; A0A3P8YNC8; -.
DR STRING; 8010.ENSELUP00000018113; -.
DR Ensembl; ENSELUT00000040453.2; ENSELUP00000018113.1; ENSELUG00000017685.2.
DR GeneID; 105017172; -.
DR KEGG; els:105017172; -.
DR GeneTree; ENSGT00390000005780; -.
DR OrthoDB; 167603at2759; -.
DR Proteomes; UP000265140; LG17.
DR Bgee; ENSELUG00000017685; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008568; EMC3.
DR InterPro; IPR002809; EMC3/TMCO1.
DR PANTHER; PTHR13116:SF10; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR13116; UNCHARACTERIZED; 1.
DR Pfam; PF01956; EMC3_TMCO1; 1.
DR PIRSF; PIRSF010045; DUF850_TM_euk; 1.
DR SMART; SM01415; DUF106; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 261 AA; 29905 MW; D6C66005762D3318 CRC64;
MAEPELLLDS NIRLWVVLPI VFITFLVGVI RHYVSILLQS DKKLTLEQVS DSQVLIRSRI
LRENGKYIPK QSFLMRKFYF NNQEDGFFKK TKRKVVPPSP MTDPSMLTDM MKGNVTNVLP
MILIGGWINW TFSGFVTTKV PFPLTLRFKP MLQQGIELLS LDASWVSSAS WYFLNVFGLR
SMYSLILGQD NGADQSRIMQ EQMSGAAMAM PADTNKAFKA EWEALELTDH QWALESVEEE
LMSRELDLDG MFSRELPTGI F
//
