ID   A0A3P8YPM0_ESOLU        Unreviewed;       790 AA.
AC   A0A3P8YPM0;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   02-DEC-2020, sequence version 2.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=MTSS I-BAR domain containing 1 {ECO:0000313|Ensembl:ENSELUP00000018082.2};
GN   Name=MTSS1 {ECO:0000313|Ensembl:ENSELUP00000018082.2};
OS   Esox lucius (Northern pike).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC   Esocidae; Esox.
OX   NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000018082.2, ECO:0000313|Proteomes:UP000265140};
RN   [1] {ECO:0000313|Ensembl:ENSELUP00000018082.2, ECO:0000313|Proteomes:UP000265140}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25069045;
RA   Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA   von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT   "The genome and linkage map of the northern pike (Esox lucius): conserved
RT   synteny revealed between the salmonid sister group and the Neoteleostei.";
RL   PLoS ONE 9:e102089-e102089(2014).
RN   [2] {ECO:0000313|Ensembl:ENSELUP00000018082.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3P8YPM0; -.
DR   Ensembl; ENSELUT00000027857.2; ENSELUP00000018082.2; ENSELUG00000017698.2.
DR   GeneTree; ENSGT00950000183156; -.
DR   InParanoid; A0A3P8YPM0; -.
DR   OMA; MGKGSDP; -.
DR   Proteomes; UP000265140; LG10.
DR   Bgee; ENSELUG00000017698; Expressed in brain and 10 other cell types or tissues.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   CDD; cd07643; I-BAR_IMD_MIM; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MTSS1/MTSS2.
DR   InterPro; IPR003124; WH2_dom.
DR   PANTHER; PTHR15708; ACTIN BUNDLING/MISSING IN METASTASIS-RELATED; 1.
DR   PANTHER; PTHR15708:SF10; PROTEIN MTSS 1; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51338; IMD; 1.
DR   PROSITE; PS51082; WH2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT   DOMAIN          1..254
FT                   /note="IMD"
FT                   /evidence="ECO:0000259|PROSITE:PS51338"
FT   DOMAIN          763..779
FT                   /note="WH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51082"
FT   REGION          255..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          624..758
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        255..338
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..393
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        624..640
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        702..727
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   790 AA;  85161 MW;  8A96ACCD831D50B4 CRC64;
     METVIERECS ALGGLFQTVI GDMKSSYPVW DDFISKAGKL QSQLRTTVVA VAAFLEAFQK
     VADLATGSRG GTRDIGSALT RMCMRHRSIE AKLRQFSVVF IDCLINPLQD QMEEWKRVAN
     TLDKDHAKEY KKARQEIKKK SSDTLKLQKK AKKADVFGRG DIQPQLDSAM QDVSDKYLLL
     EETEKQAVRK ALVEERSRFC TFVSMLRPVV EEEMSMLGEI THLQTLTDDL KALTMDPHKL
     PPASEQVILD LKGSESSWSY QTPPSSPSTT ASRKSSMCSS LNSVNSSDSR SSGSHCHSPT
     SHYRYRSSAL PQQGPARLSS VSSHDSGFIS QDAYQSKSPS PMPPDGHPQT SGSSSSAVSE
     TCQPVSEGSS SSSSSSPASS KETCSSTRVD QLSNGYDHHP HLHHGPSTAP DLCGGGIQEG
     YPHLPPSSPS STPLASPSSP SSPMWAWSKP GSALLVDRPP YCTQETGMIP SSKVPTWKDW
     AKPGPYDQPM VNTLRRTKKE TPDPSSPPAT TPGDEPQRAR GTNAVTTPKE EAHEDLALAL
     ALGLQLDIQR SSRDSLQCSS GYSTQSTTPC CSEDTIPSQV SDYDYFSVSG DQETDQLDFD
     KSSTIPRNSD ISQSYRRMFQ AKRPASTAGI PSTAPSPASI VTPGVATIRR TPSSKPHLRR
     PSGGLGLGPI PIKPPMIPVK TPTVPEHPGG FIGGEGEGAG TLSPQSPRSS PGDNGLVSSR
     SARDTQAPSD PPSPPPQPGG RLSEWDHEAL PEVQEEEIGC GEGEDVLLAI RRGVKLKKTM
     TNDRSAPRIV
//