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Database: UniProt
Entry: A0A3P8YY99_ESOLU
LinkDB: A0A3P8YY99_ESOLU
Original site: A0A3P8YY99_ESOLU 
ID   A0A3P8YY99_ESOLU        Unreviewed;       248 AA.
AC   A0A3P8YY99;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   02-DEC-2020, sequence version 2.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Syntaxin-2 {ECO:0000313|Ensembl:ENSELUP00000021138.2};
GN   Name=STX2 {ECO:0000313|Ensembl:ENSELUP00000021138.2};
OS   Esox lucius (Northern pike).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC   Esocidae; Esox.
OX   NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000021138.2, ECO:0000313|Proteomes:UP000265140};
RN   [1] {ECO:0000313|Ensembl:ENSELUP00000021138.2, ECO:0000313|Proteomes:UP000265140}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25069045;
RA   Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA   von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT   "The genome and linkage map of the northern pike (Esox lucius): conserved
RT   synteny revealed between the salmonid sister group and the Neoteleostei.";
RL   PLoS ONE 9:e102089-e102089(2014).
RN   [2] {ECO:0000313|Ensembl:ENSELUP00000021138.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the syntaxin family.
CC       {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR   AlphaFoldDB; A0A3P8YY99; -.
DR   STRING; 8010.ENSELUP00000021138; -.
DR   Ensembl; ENSELUT00000031746.2; ENSELUP00000021138.2; ENSELUG00000020251.2.
DR   GeneTree; ENSGT01030000234627; -.
DR   OrthoDB; 2876074at2759; -.
DR   Proteomes; UP000265140; LG13.
DR   Bgee; ENSELUG00000020251; Expressed in heart and 11 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd00179; SynN; 1.
DR   Gene3D; 1.20.5.110; -; 1.
DR   Gene3D; 1.20.58.70; -; 1.
DR   InterPro; IPR010989; SNARE.
DR   InterPro; IPR045242; Syntaxin.
DR   InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR   InterPro; IPR006011; Syntaxin_N.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR19957; SYNTAXIN; 1.
DR   PANTHER; PTHR19957:SF36; SYNTAXIN-2; 1.
DR   Pfam; PF05739; SNARE; 1.
DR   Pfam; PF00804; Syntaxin; 1.
DR   SMART; SM00503; SynN; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   SUPFAM; SSF47661; t-snare proteins; 1.
DR   PROSITE; PS00914; SYNTAXIN; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265140}.
FT   DOMAIN          163..225
FT                   /note="T-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50192"
SQ   SEQUENCE   248 AA;  28730 MW;  B2FDB36C4BBE7835 CRC64;
     MEVFFRRVED IRGLIDKISS GVEEVRKKHG MMLSAPNPDE KAKDELVQLT SDIKTNANSV
     RVKLKSMEQS LPKEDVSNRA SVDFRIQKTQ YTVLSRKFVE VMTQYNETQV SFRERSKGRI
     QRQLEITGRV TSDEELEDML ESGNPSIFTS DIISDSQITR QALNEIESRH QDIIRLESSI
     MELHAVFMDM AMLVENQGDM VNNIEKNVSN AVEYIGRAKE ETKKAVRYQR KSRRLKTYYV
     LVVMVKNK
//
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