ID A0A3P8Z322_ESOLU Unreviewed; 300 AA.
AC A0A3P8Z322;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Forkhead box protein H1 {ECO:0000313|Ensembl:ENSELUP00000022863.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000022863.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000022863.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000022863.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_010889848.1; XM_010891546.3.
DR AlphaFoldDB; A0A3P8Z322; -.
DR STRING; 8010.ENSELUP00000022863; -.
DR Ensembl; ENSELUT00000042444.2; ENSELUP00000022863.1; ENSELUG00000000945.2.
DR KEGG; els:105022818; -.
DR GeneTree; ENSGT01030000234863; -.
DR InParanoid; A0A3P8Z322; -.
DR OrthoDB; 4152961at2759; -.
DR Proteomes; UP000265140; LG10.
DR Bgee; ENSELUG00000000945; Expressed in ovary and 4 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47316; FORKHEAD BOX PROTEIN H1; 1.
DR PANTHER; PTHR47316:SF1; FORKHEAD BOX PROTEIN H1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 25..130
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 25..130
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 300 AA; 33787 MW; E35DC355164A9855 CRC64;
MTEKISLQAP SNGVPQRKHR RYGKNKSITY LGLVANVIQD SPDKMLTFTQ LMDRLEAFIS
GDRKGIENNI RVCLSSNDCF VKVPADPYVT YSKKNLWKFD ESRITAKMAR RNFKGILDQF
PDLSTKVRKE SRERKFEATD RIASLHSPTQ ELDCAPIQRK TEGKFTSSFS IDSILNTGSS
RLCPQARQLP VVSRVPTDQV LLCAESGIGT KRGMSWDRPP VETCRAPCPG ESYPSYVIPR
QSYPVNGGRI APNMMRMGSE PSYPVYIRPG VALCFSDRFS RCEVGYPVWA TDNPAPYLLL
//
