ID   A0A3P8Z3S3_ESOLU        Unreviewed;       672 AA.
AC   A0A3P8Z3S3;
DT   13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT   02-DEC-2020, sequence version 2.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Protein shisa-7 {ECO:0000313|Ensembl:ENSELUP00000023370.2};
OS   Esox lucius (Northern pike).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC   Esocidae; Esox.
OX   NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000023370.2, ECO:0000313|Proteomes:UP000265140};
RN   [1] {ECO:0000313|Ensembl:ENSELUP00000023370.2, ECO:0000313|Proteomes:UP000265140}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25069045;
RA   Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA   von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT   "The genome and linkage map of the northern pike (Esox lucius): conserved
RT   synteny revealed between the salmonid sister group and the Neoteleostei.";
RL   PLoS ONE 9:e102089-e102089(2014).
RN   [2] {ECO:0000313|Ensembl:ENSELUP00000023370.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3P8Z3S3; -.
DR   STRING; 8010.ENSELUP00000023370; -.
DR   Ensembl; ENSELUT00000034536.2; ENSELUP00000023370.2; ENSELUG00000022211.2.
DR   GeneTree; ENSGT00940000162254; -.
DR   InParanoid; A0A3P8Z3S3; -.
DR   OMA; GNLHHHF; -.
DR   OrthoDB; 4106833at2759; -.
DR   Proteomes; UP000265140; LG10.
DR   Bgee; ENSELUG00000022211; Expressed in brain and 3 other cell types or tissues.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026910; Shisa.
DR   PANTHER; PTHR31774:SF2; PROTEIN SHISA-7; 1.
DR   PANTHER; PTHR31774; PROTEIN SHISA-9-RELATED; 1.
DR   Pfam; PF13908; Shisa; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..672
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5027745161"
FT   TRANSMEM        210..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          52..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          608..629
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          651..672
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   672 AA;  73290 MW;  2AE422D375AC5526 CRC64;
     MRSRTYRRMF STSLIFFLVS GLILSAVTVT VDQRSSDGGP RGTTLFLLTG FGNKPMPPPP
     GGSKVAPKAA EMEEAQDSGL KGVETLPVPL PQIMLPPNMT AADALKPPLG AAQVAPPPRR
     LVDVDMCRAY YDVMGQLDQA FNCSKGTYIY CCGTCHYRYC CDHQRSRLDQ ELCTNYKSPV
     WANTQPLSTI PPGNRGDPDS EQLKQSNSTA YVIGGVISFT LVVAVGIKVA FHKMSRRPRN
     RDINMPRALV DILRSQSSPV QQGERNNSTV LTTATTGDSM GRPTKNLYAP VLQSKDNRIG
     NLHQNFIQVS DSSPKHSATM ERVPRMNNTQ LASTGTVLTS KHNNSSSLHS HPHPSFSHSF
     HNLDQLPPSY ETVMKPEINR YSSLKRLEKD LDEYSGYYTS KRRPNNAPPS FHSSQHHLHW
     GGDYTLGARG TLPLQTSRPR IQVPTSTPNP YPLPAQPSGY QASFDKPPRR VMSQDQLLAL
     VEGNTLSRLS KNQQHQYYKA MTTSKSSTSQ TLRKSHERLL VSPDRLEDRM VTMGLPGMGG
     MAGMGGMADF GGMGVPTMGR LSHKAQSQQN VCITPSLDRH HMIKMNSHPT SGHELERSTA
     GHPVGSWGEP HGSGMGLGPG NGAGNIGGHN ARRMAFATKR QNTIEQLQYI PGGGGGGGGQ
     ALRTASKNEV TV
//