ID A0A3P8Z6C1_ESOLU Unreviewed; 1052 AA.
AC A0A3P8Z6C1;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized LOC105020330 {ECO:0000313|Ensembl:ENSELUP00000023752.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000023752.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000023752.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000023752.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_010885572.1; XM_010887270.3.
DR AlphaFoldDB; A0A3P8Z6C1; -.
DR STRING; 8010.ENSELUP00000023752; -.
DR Ensembl; ENSELUT00000035015.2; ENSELUP00000023752.1; ENSELUG00000022591.2.
DR GeneID; 105020330; -.
DR KEGG; els:105020330; -.
DR GeneTree; ENSGT00940000156038; -.
DR InParanoid; A0A3P8Z6C1; -.
DR OMA; WNDEDEC; -.
DR OrthoDB; 5347495at2759; -.
DR Proteomes; UP000265140; LG23.
DR Bgee; ENSELUG00000022591; Expressed in ovary and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR14002:SF52; -; 1.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR SMART; SM00181; EGF; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SMART; SM00241; ZP; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1019..1039
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..362
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 663..702
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 723..977
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 1052 AA; 117533 MW; DD836B38E1D0B487 CRC64;
MFVQVTPTKT TGPLRLTSTC QSLLVGDVRS FFTFPFILFV LVPLNTIYFG SCSNFTFSIC
WKISSWPEGN IWLNNNKLKS IWRPDTFSSL TVATTVEHNL TLQYGAVVHE WTFSILPSSN
TIMFISKQKP EEQPVSALED LKMFSVDEVF ACENSPLYLY RDLDFILMLG HTVRHPLKLE
SRTASMLLVT WNKAPPLAPA DPAPSHSVSL YHSEMKAYAV LSVDSTRSSH YRFTGLESCT
PHVACVGIAG SHSLSCLSTI TDPDVPRHFQ VTLRDTSSVT VSWGCPENCK YSLFLVTVFY
LNGTNHILEE RSYKHTSDSF VFTQSNLTSC SRVRFGLQTV CKAGMDTRRS KMLLIDGNAV
QSEIEDLRQT GSGPENYTLS WMVRNTSSVA AFRIYHQGVL HTTTLLTSHT VAALQPCSQY
TARLEALCGE NVVMSAKTVR ARTGPRGVSE LSYRPKDSTA LWMAGTGSPV SFQYRLAYVN
GSTIHEGRLM EPWLHLPGLV EGWPYALDVW EECDGEWSAD PALVCFNGAN VPINHTVLPP
VPSVSTNEDL GLMFPRPSLA IVVPWSLGAD LQDPRSEPRA ELERVVTNKL EKLLEGYPGK
INIQLVAFEN LEVENRTKIT FQVFDASTSS ENLLLPIEVQ LKHIQPPQSF NITIDDGIIY
WDDPDECASP DQNKCEPGSV CINTLDSYSC VCPHGFYDVG PIFNPSPSTS SYPICREKGM
FAQCLDGFMV GGIAKTFLMD YFGGNVNIVL NAGQCTMNES ETLYHFRMLR TPPQCGTTRL
VNRTDIEFRN TLTVTLSRDE IITRRDLKVI WKCIYPRSHV HNAQINLDLE WITSYSVLQY
NSSLELGLAM TMYSDDSFSH SYRDAITLGY SDVLFFEVAL LTNNTFASEV LLEVVSCWAT
ESPDPQDETK GFFLQHSCPT DTTFEWLSVN GAAQESRFSV QMFALPRELP IYMHCMAKIC
SPFEDCTKDC VTQRVSKRSI TKWGVDPRRS AIVSVGPLTV TSSETPGTKS SNWQEVGTMA
FVVGGSISML MLTVLGVSLT KAFMNYYERA RP
//
