ID A0A3P8Z6P0_ESOLU Unreviewed; 347 AA.
AC A0A3P8Z6P0;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Leucine rich repeat containing 59 {ECO:0000313|Ensembl:ENSELUP00000024471.1};
OS Esox lucius (Northern pike).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Esociformes;
OC Esocidae; Esox.
OX NCBI_TaxID=8010 {ECO:0000313|Ensembl:ENSELUP00000024471.1, ECO:0000313|Proteomes:UP000265140};
RN [1] {ECO:0000313|Ensembl:ENSELUP00000024471.1, ECO:0000313|Proteomes:UP000265140}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25069045;
RA Rondeau E.B., Minkley D.R., Leong J.S., Messmer A.M., Jantzen J.R.,
RA von Schalburg K.R., Lemon C., Bird N.H., Koop B.F.;
RT "The genome and linkage map of the northern pike (Esox lucius): conserved
RT synteny revealed between the salmonid sister group and the Neoteleostei.";
RL PLoS ONE 9:e102089-e102089(2014).
RN [2] {ECO:0000313|Ensembl:ENSELUP00000024471.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_010864332.1; XM_010866030.3.
DR AlphaFoldDB; A0A3P8Z6P0; -.
DR STRING; 8010.ENSELUP00000024471; -.
DR Ensembl; ENSELUT00000035972.2; ENSELUP00000024471.1; ENSELUG00000023258.2.
DR GeneID; 105007195; -.
DR KEGG; els:105007195; -.
DR GeneTree; ENSGT00940000165932; -.
DR InParanoid; A0A3P8Z6P0; -.
DR OMA; SWIREQE; -.
DR OrthoDB; 3109191at2759; -.
DR Proteomes; UP000265140; LG06.
DR Bgee; ENSELUG00000023258; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265140};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 250..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 159..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..203
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 39327 MW; 8C8BA22E20258EE5 CRC64;
MSKSKVLNLK DKIDGNEMDL SLCNLTEVPV KELAAFPKVT VLDLSCNNIS SLPLEFCSLS
HLIKVDLSKN QLTVLPDDLG RLSNLQQLDL YNNKLTILPV SFSQLKNLKW LDLKDNPLEI
NLAKAAGDCL DEKQCKQCAV RVLQHMRILQ EEVDKERERR LQKEKELEKK KEAKQREREA
KEREARKREK AEEKERKRKE YNAHIAAMAV QEQKNKRKEE KRRRTGQAVA DKKAAVESAP
KAQRHTLIGL LFKLLLLLLL GLAGVVGVCQ LTGLNDEAMC VPVNSAVGDG LSWVREQKVD
LKVRELVQEV DIRARELLQK LSSLAPQLLK PLVPTATVTE PVETVEN
//
